IHC (Immunohiostchemistry)
Mouse anti-Human, mouse Epithelial cell adhesion molecule, EP-CAM Monoclonal Antibody | anti-EP-CAM antibody
Monoclonal Anti- Epithelial cell adhesion molecule, EP-CAM
Gene Names
EPCAM; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1
Reactivity
Human, mouse
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Protein affinity purified
Synonyms
Epithelial cell adhesion molecule, EP-CAM, Antibody; Monoclonal Anti- Epithelial cell adhesion molecule, EP-CAM; Monoclonal Anti- Epithelial cell adhesion molecule; EP-CAM; anti-EP-CAM antibody
Host
Mouse
Reactivity
Human, mouse
Clonality
Monoclonal
Isotype
IgM
Clone Number
3-E1-E2
Purity/Purification
Protein affinity purified
Form/Format
Liquid; In TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.
Applicable Applications for anti-EP-CAM antibody
FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant EP-CAM protein.
Preparation and Storage
Store at 4°C after thawing (1 week). Aliquot and store at -20°C for long term (at least one year). Avoid repeated freeze and thaw cycles.
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-EP-CAM antibody
Epithelial cell adhesion molecule (Ep-CAM) is a pan-epithelial differentiation antigen. [1]It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signalling and polarity. It has been used as an immunotherapeutic target in the treatment of gastrointestinal, urological and other carcinomas. [2]It is expressed in undifferentiated pluripotent stem cells. [3] and it is being used as a target for immunotherapy treatment of human carcinomas.
References
1. Calabrese G, Crescenzi C, Morizio E, Palka G, Guerra E, Alberti S (Apr 2001). "Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization". Cytogenet Cell Genet 92 (1-2): 164-5. 2. Chaudry MA, Sales K, Ruf P, Lindhofer H, Winslet MC (April 2007). "EpCAM an immunotherapeutic target for gastrointestinal malignancy: current experience and future challenges". Br. J. Cancer 96 (7): 1013-9. 3. Sundberg, M; Jansson, L; Ketolainen, J; Pihlajamäki, H; Suuronen, R; Skottman, H; Inzunza, J; Hovatta, O et al. (2009). "CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells.". Stem cell research 2 (2): 113-24.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Epithelial cell adhesion molecule
NCBI Official Synonym Full Names
epithelial cell adhesion molecule
NCBI Official Symbol
EPCAM
NCBI Official Synonym Symbols
ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1
NCBI Protein Information
epithelial cell adhesion molecule; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)
UniProt Protein Name
Epithelial cell adhesion molecule
UniProt Gene Name
EPCAM
UniProt Synonym Gene Names
GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1; Ep-CAM; EGP; EGP314; hEGP314
UniProt Entry Name
EPCAM_HUMAN
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Product Notes
The EP-CAM epcam (Catalog #AAA58852) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Anti- Epithelial cell adhesion molecule, EP-CAM reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Epithelial cell adhesion molecule, EP-CAM can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the EP-CAM epcam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Epithelial cell adhesion molecule, EP-CAM, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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