Mouse anti-EBV Epstein-Barr Virus (LMP-1) Monoclonal Antibody | anti-LMP-1 antibody

Epstein-Barr Virus (LMP-1)

Cat. Num. AAA215347

• Reactivity: EBV
• Applications: Immunohistochemistry, Western Blot, Immunofluorescence
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Epstein-Barr Virus (LMP-1), Antibody; Epstein-Barr Virus (LMP-1); EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1; Human Herpesvirus 4 (HHV4); anti-LMP-1 antibody

• Host: Mouse
• Reactivity: EBV
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: CS1-4
• Specificity: This antibody is a mixture of four different monoclonal antibodies. This antibody is specific to 60kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the EBV. Each clone reacts with different epitopes on the hydrophilic C-terminus of the cytoplasmic domain of LMP-1. This antibody stains strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. EBV, also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness.
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

• Applicable Applications for anti-LMP-1 antibody: IHC (Immunohistochemistry), WB (Western Blot), IF (Immunofluorescence)
• Positive Control: EBV-infected cells. Tissues.
• Immunogen: Recombinant fusion protein containing the sequence of bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP
• Preparation and Storage: Antibody with azide: store at 2 to 8 degrees C. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human Hodgkin's Lymphoma stained with EBV Mouse Monoclonal Antibody (CS1-4).)

References

Rowe M, Evans HS, Young LS, Hennessy K, Kieff E, Rickinson AB. Monoclonal antibodies to the latent membrane protein of Epstein-Barr virus reveal heterogeneity of the protein and inducible expression in virus-transformed cells. J Gen Virol 1987;68:1575-86.