Mouse anti-Human, mouse ERGIC53 Monoclonal Antibody | anti-ERGIC53 antibody

ERGIC53 Monoclonal Antibody

Cat. Num. AAA41014

• Reactivity: Human, mouse
• Applications: Immunocytochemistry, Western Blot, ELISA
• Purity: ERGIC53 Monoclonal Antibody is Protein A purified.
• Synonyms: ERGIC53, Antibody; ERGIC53 Monoclonal Antibody; anti-ERGIC53 antibody

• Host: Mouse
• Reactivity: Human, mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Specificity: At least two isoforms of ERGIC53 are known to exist.
• Purity/Purification: ERGIC53 Monoclonal Antibody is Protein A purified.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)

• Applicable Applications for anti-ERGIC53 antibody: ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Immunogen: Mouse monoclonal ERGIC53 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ERGIC53.
• Buffer: ERGIC53 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: ERGIC53 Monoclonal antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

IHC (Immunohiostchemistry)

(Immunocytochemistry of ERGIC53 in HL60 cells with ERGIC53 antibody at 5 ?g/ml.)

WB (Western Blot)

(Western blot analysis of ERGIC53 in HL60 cell lysate with ERGIC53 antibody at 1 ?g/mL in (A) the absence and (B) the presence of blocking buffer.)

Related Product Information for anti-ERGIC53 antibody

ERGIC53 Monoclonal Antibody: ERGIC53, also known as lectin mannose-binding 1 (LMAN1) protein is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Product Categories/Family for anti-ERGIC53 antibody

Homeostasis

References

Schindler R, Itin C, Zerial M, et al. ERGIC-53, a membrane protein of the ER-Golgi intermediate compartment, carries an ER retention motif. Eur. J. Cell Biol. 1993; 61:1-9.

NCBI and Uniprot Product Information

• NCBI GI #: 5031873
• Molecular Weight: Predicted: 56 kDa