Rabbit anti-Human FABP4 Monoclonal Antibody | anti-FABP4 antibody

Recombinant Anti-FABP4 Antibody, Rabbit Monoclonal

Cat. Num. AAA255519

• Gene Names: FABP4; aP2; ALBP; AFABP; A-FABP; HEL-S-104
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry
• Purity: Protein A
• Synonyms: FABP4, Antibody; Recombinant Anti-FABP4 Antibody, Rabbit Monoclonal; FABP4/ALBP/A-FABP Antibody, Rabbit MAb; fatty acid binding protein 4, adipocyte; Anti-A-FABP Antibody; Anti-AFABP Antibody; Anti-ALBP Antibody; Anti-aP2 Antibody; Anti-HEL-S-104 Antibody; anti-FABP4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone Number: 001
• Specificity: Human FABP4/ALBP/A-FABP.; No cross-reactivity in ELISA with Human FABP6; Has cross-reactivity in ELISA with Mouse FABP3
• Purity/Purification: Protein A
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-FABP4 antibody: FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
• Antibody Type: Recombinant Antibody
• Immunogen: Recombinant Human FABP4/ALBP/A-FABP protein
• Conjugation: Unconjugated
• Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human FABP4/ALBP/A-FABP (rh FABP4/ALBP/A-FABP).
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of Human FABP4 expression on Hela cells. The cells were treated according to manufacturer's manual (BD Pharmingen'), stained with purified anti-Human FABP4, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.)

IHC (Immunohiostchemistry)

(Immunochemical staining of human FABP4 in human appendix with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)

IHC (Immunohistochemistry)

(Immunochemical staining of human FABP4 in human lung cancer with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)

Related Product Information for anti-FABP4 antibody

Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.

Product Categories/Family for anti-FABP4 antibody

Early Mesodermal Lineage Markers

References

van Dongen, M.J. et al., 2002, J Am Chem Soc. 124 (40): 11874-80. Coll, B. et al., 2008, Atherosclerosis 199 (1):147-53. Hoashi, S. et al., 2008, BMC Genet. 9 :84. Cai, H. et al., 2010, Bioorg Med Chem Lett 20 (12):3675-9.

NCBI and Uniprot Product Information

• NCBI GI #: 119781
• NCBI GeneID: 2167
• UniProt Accession #: P15090; Q6IBA1
• Molecular Weight: 132
• NCBI Official Full Name: Fatty acid-binding protein, adipocyte
• NCBI Official Synonym Full Names: fatty acid binding protein 4, adipocyte
• NCBI Official Symbol: FABP4
• NCBI Official Synonym Symbols: aP2; ALBP; AFABP; A-FABP; HEL-S-104
• NCBI Protein Information: fatty acid-binding protein, adipocyte; fatty acid-binding protein 4; adipocyte lipid-binding protein; epididymis secretory protein Li 104; adipocyte-type fatty acid-binding protein
• UniProt Protein Name: Fatty acid-binding protein, adipocyte
• UniProt Gene Name: FABP4
• UniProt Synonym Gene Names: ALBP; A-FABP; AFABP
• UniProt Entry Name: FABP4_HUMAN