WB (Western Blot)
(Western BlotPositive WB detected in: THP-1 whole cell lysateAll lanes: CD32 antibody at 1:1000SecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 35, 36 kDaObserved band size: 45 kDa)
FCGR2A recombinant antibody
FCGR2A Antibody
Gene Names
FCGR2A; CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-chromatography
Synonyms
FCGR2A, Recombinant Antibody; FCGR2A Antibody; Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32); FCGR2A; CD32 FCG2 FCGR2A1 IGFR2; FCGR2A recombinant antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity-chromatography
Form/Format
Liquid
Applicable Applications for FCGR2A recombinant antibody
WB (Western Blot), ELISA
Immunogen
A synthesized peptide derived from human CD32
Immunogen Species
Homo sapiens (Human)
Research Areas
Immunology ; Stem Cells
Storage Buffer
Rabbit IgG in phosphate buffered saline, PH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Conjugate
Non-conjugated
Product type
Recombinant Antibody
Preparation and Storage
Upon receipt, store at -20 degree or -80 degree Avoid repeated freeze.
WB (Western Blot)
(Western BlotPositive WB detected in: THP-1 whole cell lysateAll lanes: CD32 antibody at 1:1000SecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 35, 36 kDaObserved band size: 45 kDa)
WB (Western Blot)
(Western BlotPositive WB detected in: THP-1 whole cell lysateAll lanes: CD32 antibody at 1:1000SecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 35, 36 kDaObserved band size: 45 kDa)
Related Product Information for FCGR2A recombinant antibody
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Description: The recombinant FCGR2A monoclonal antibody is produced through a series of steps: first, sequencing the FCGR2A monoclonal antibody gene; second, incorporating the gene into a plasmid vector; third, introducing the recombinant vector into a host cell line; fourth, and finally, purifying the FCGR2A recombinant monoclonal antibody from the cell culture supernatant using affinity chromatography. The FCGR2A monoclonal antibody is derived from the FCGR2A antibody-producing hybridomas, using a synthesized peptide from human FCGR2A as the immunogen. The recombinant FCGR2A monoclonal antibody is highly recommended for ELISA and WB applications to detect human FCGR2A protein. The FCGR2A protein, also known as CD32a, is a member of the Fc gamma receptor family and plays a key role in the immune response. Specifically, it is an activating receptor expressed on the surface of certain immune cells, such as macrophages, monocytes, and dendritic cells, where it binds to the Fc portion of immunoglobulin G (IgG) antibodies. This binding triggers a signaling cascade that leads to various cellular responses, including phagocytosis, antibody-dependent cell-mediated cytotoxicity (ADCC), and the release of inflammatory cytokines. The FCGR2A protein is thus an important mediator of the body's defense against pathogens and foreign substances.
Description: The recombinant FCGR2A monoclonal antibody is produced through a series of steps: first, sequencing the FCGR2A monoclonal antibody gene; second, incorporating the gene into a plasmid vector; third, introducing the recombinant vector into a host cell line; fourth, and finally, purifying the FCGR2A recombinant monoclonal antibody from the cell culture supernatant using affinity chromatography. The FCGR2A monoclonal antibody is derived from the FCGR2A antibody-producing hybridomas, using a synthesized peptide from human FCGR2A as the immunogen. The recombinant FCGR2A monoclonal antibody is highly recommended for ELISA and WB applications to detect human FCGR2A protein. The FCGR2A protein, also known as CD32a, is a member of the Fc gamma receptor family and plays a key role in the immune response. Specifically, it is an activating receptor expressed on the surface of certain immune cells, such as macrophages, monocytes, and dendritic cells, where it binds to the Fc portion of immunoglobulin G (IgG) antibodies. This binding triggers a signaling cascade that leads to various cellular responses, including phagocytosis, antibody-dependent cell-mediated cytotoxicity (ADCC), and the release of inflammatory cytokines. The FCGR2A protein is thus an important mediator of the body's defense against pathogens and foreign substances.
Product Categories/Family for FCGR2A recombinant antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-a isoform 1
NCBI Official Synonym Full Names
Fc fragment of IgG, low affinity IIa, receptor (CD32)
NCBI Official Symbol
FCGR2A
NCBI Official Synonym Symbols
CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-a; fcRII-a; fc-gamma-RIIa; fc-gamma RII-a; igG Fc receptor II-a; Immunoglobulin G Fc receptor II
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-a
UniProt Gene Name
FCGR2A
UniProt Synonym Gene Names
CD32; FCG2; FCGR2A1; IGFR2; IgG Fc receptor II-a; Fc-gamma-RIIa; FcRII-a
UniProt Entry Name
FCG2A_HUMAN
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Product Notes
The FCGR2A fcgr2a (Catalog #AAA243816) is a Recombinant Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FCGR2A Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FCGR2A can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FCGR2A fcgr2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCGR2A, Monoclonal Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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