IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded Human Pancreas stained with Ferritin, Light Chain Monoclonal Antibody (FTL/1388).)
Mouse Ferritin, Light Chain (FTL) Monoclonal Antibody | anti-FTL antibody
Ferritin, Light Chain (FTL) (Microglia Marker)
Gene Names
FTL; LFTD; NBIA3
Reactivity
Human. Others not known.
Applications
Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
Ferritin, Light Chain (FTL), Antibody; Ferritin, Light Chain (FTL) (Microglia Marker); Ferritin L chain; Ferritin L subunit; Ferritin light chain; Ferritin light polypeptide; FTL; LFTD; NBIA3; anti-FTL antibody
Host
Mouse
Reactivity
Human. Others not known.
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
FTL/1388
Specificity
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
175
Applicable Applications for anti-FTL antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant human FTL protein fragment (aa 38-165)
Cellular Localization
Cytoplasmic
Hu-chromosome Location
19q13.33
Positive Control
HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded Human Pancreas stained with Ferritin, Light Chain Monoclonal Antibody (FTL/1388).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded Human Pancreas stained with Ferritin, Light Chain Monoclonal Antibody (FTL/1388).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded Human Pancreas stained with Ferritin, Light Chain Monoclonal Antibody (FTL/1388).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded Human Pancreas stained with Ferritin, Light Chain Monoclonal Antibody (FTL/1388).)
References
Y. Kaneko, T. Kitamoto, J. Tateishi, K. Yamaguchi. Ferritin immunohistochemistry as a marker for microglia. Acta Neuropathologica. 1989, Volume 79; 129-136.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19-25kDa
NCBI Official Full Name
ferritin light chain
NCBI Official Synonym Full Names
ferritin light chain
NCBI Official Symbol
FTL
NCBI Official Synonym Symbols
LFTD; NBIA3
NCBI Protein Information
ferritin light chain
UniProt Protein Name
Ferritin light chain
UniProt Gene Name
FTL
UniProt Synonym Gene Names
Ferritin L subunit
Similar Products
Product Notes
The FTL ftl (Catalog #AAA62990) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Ferritin, Light Chain (FTL) (Microglia Marker) reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's Ferritin, Light Chain (FTL) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the FTL ftl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ferritin, Light Chain (FTL), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.