Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
NFPRb
Specificity
This antibody recognizes human FPR1 at the cytoplasmic C-terminal aa 338- STLPSAEVELQAK-350. It is sensitive to C-terminal tail phosphorylation. It does not recognize human FPR2.
Purity/Purification
Protein G purified
Form/Format
100ug protein G-purified antibody in PBS pH 7.4
Concentration
1.06 mg/ml (varies by lot)
Sequence Length
350
Applicable Applications for anti-FPR1 antibody
IF (Immunofluorescence), IB (Immunoblot)
Antigen
His-tagged recombinant FPR1 (human neutrophil N-formyl peptide receptor 1) expressed in and purified from Sf9 cells.
Appearance
Clear liquid
Dilution Instructions
Dilute in PBS or medium that is identical to that used in the assay system.
Preservative
None
Preparation and Storage
This product is stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Related Product Information for anti-FPR1 antibody
Formyl peptide receptors (FPR) are G protein-coupled receptors that are activated by different agonists included N-formylated peptides originating from bacteria and mitochondria. In humans, the FPR family includes the high affinity FPR1, the low affinity FPR2/ALX (previously known as FPRL1 or ALX) and FPR3. Human FPR1 is important for phagocyte chemotaxis, superoxide production, and degranulation, and helps direct phagocytes to sites of infection. Functional FPR1expression has been demonstrated on fibroblasts, bone marrow mesenchymal stem cells, A549 lung cells, HEP-G2 hepatoma cells, and on several types of epithelial cells.
Product Categories/Family for anti-FPR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,446 Da
NCBI Official Full Name
fMet-Leu-Phe receptor
NCBI Official Synonym Full Names
formyl peptide receptor 1
NCBI Official Symbol
FPR1
NCBI Official Synonym Symbols
FPR; FMLP
NCBI Protein Information
fMet-Leu-Phe receptor
UniProt Protein Name
fMet-Leu-Phe receptor
UniProt Gene Name
FPR1
UniProt Synonym Gene Names
fMLP receptor; FPR
UniProt Entry Name
FPR1_HUMAN
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Product Notes
The FPR1 fpr1 (Catalog #AAA47759) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FPR1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IB (Immunoblot). Researchers should empirically determine the suitability of the FPR1 fpr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FPR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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