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product-image-AAA255043_IHC13.png IHC (Immunohiostchemistry) (Immunochemical staining of human CX3CL1 in human kidney with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).)

Rabbit anti-Human Fractalkine Monoclonal Antibody | anti-CX3CL1 antibody

Recombinant Anti-Fractalkine Antibody, Rabbit Monoclonal

Gene Names
CX3CL1; NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
Reactivity
Human
Applications
Immunohistochemistry, ELISA, ELISA
Purity
Protein A
Synonyms
Fractalkine, Antibody; Recombinant Anti-Fractalkine Antibody, Rabbit Monoclonal; Fractalkine/CX3CL1 Antibody, Rabbit MAb; chemokine (C-X3-C motif) ligand 1; Anti-ABCD-3 Antibody; Anti-C3Xkine Antibody; Anti-CXC3 Antibody; Anti-CXC3C Antibody; Anti-fractalkine Antibody; Anti-neurotactin Antibody; Anti-NTN Antibody; Anti-NTT Antibody; Anti-SCYD1 Antibody; anti-CX3CL1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
409
Specificity
Human Fractalkine/CX3CL1
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-CX3CL1 antibody
IHC (Immunohistochemistry), ELISA, ELISA
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Human Fractalkine/CX3CL1 protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human Fractalkine/CX3CL1 (rh Fractalkine/CX3CL1).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohiostchemistry)

(Immunochemical staining of human CX3CL1 in human kidney with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).)

product-image-AAA255043_IHC13.png IHC (Immunohiostchemistry) (Immunochemical staining of human CX3CL1 in human kidney with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).)

IHC (Immunohistochemistry)

(Immunochemical staining of human CX3CL1 in human pancreas with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).)

product-image-AAA255043_IHC15.png IHC (Immunohistochemistry) (Immunochemical staining of human CX3CL1 in human pancreas with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-CX3CL1 antibody
Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine/CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine/CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines.
Product Categories/Family for anti-CX3CL1 antibody
References
Imai T, et al. (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell. 91(4): 521-30.Papadopoulos EJ, et al. (1999) Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation. Eur J Immunol. 29 (8): 2551-9.Umehara H, et al. (2004) Fractalkine in vascular biology: from basic research to clinical disease". Arterioscler. Thromb Vasc Biol. 24 (1): 34-40.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
fractalkine isoform 1
NCBI Official Synonym Full Names
C-X3-C motif chemokine ligand 1
NCBI Official Symbol
CX3CL1
NCBI Official Synonym Symbols
NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
NCBI Protein Information
fractalkine
UniProt Protein Name
Fractalkine
UniProt Gene Name
CX3CL1
UniProt Synonym Gene Names
FKN; NTT; SCYD1
UniProt Entry Name
X3CL1_HUMAN

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Product Notes

The CX3CL1 cx3cl1 (Catalog #AAA255043) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-Fractalkine Antibody, Rabbit Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Fractalkine can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, ELISA. Researchers should empirically determine the suitability of the CX3CL1 cx3cl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fractalkine, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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