FCM/FACS (Flow Cytometry)
(FACS analysis of human Monocytes using CD15 Monoclonal Antibody (Leu-M1).)
Mouse Galectin-13 (GAL13)/Placental Protein 13 (PP13) Monoclonal Antibody | anti-GAL13 antibody
Galectin-13 (GAL13)/Placental Protein 13 (PP13)
Gene Names
LGALS13; PP13; GAL13; PLAC8
Reactivity
Human. Others not known
Applications
Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, ELISA
Synonyms
Galectin-13 (GAL13)/Placental Protein 13 (PP13), Antibody; Galectin-13 (GAL13)/Placental Protein 13 (PP13); Gal-13; GAL13; Galactoside-binding soluble lectin 13; Galectin-13; Galectin13; Lectin galactoside binding soluble 13; LGALS13; PLAC8; Placental protein 13 (PP13); Placental tissue protein 13; anti-GAL13 antibody
Host
Mouse
Reactivity
Human. Others not known
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
PP13/1165
Specificity
It recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a marker to predict preterm pre-eclampsia.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
139
Applicable Applications for anti-GAL13 antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA
Immunogen
Recombinant human Galectin-13 protein fragment (aa23-134)
Cellular Localization
Cytoplasmic & Cell Surface
Positive Control
K-562 cells. Placenta or Spleen.
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
FCM/FACS (Flow Cytometry)
(FACS analysis of human Monocytes using CD15 Monoclonal Antibody (Leu-M1).)
FCM/FACS (Flow Cytometry)
(FACS analysis of human Monocytes using CD15 Monoclonal Antibody (Leu-M1).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Placenta stained with Galectin-13 / PP13 Monoclonal Antibody (PP13/1165).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Placenta stained with Galectin-13 / PP13 Monoclonal Antibody (PP13/1165).)
References
Akolekar, R., et al. 2009. Maternal serum placental protein 13 at 11-13 weeks of gestation in preeclampsia. Prenat. Diagn. 29: 1103-1108.Koster, M.P., et al. 2009. Placental protein 13 as a first trimester screening marker for aneuploidy. Prenat. Diagn. 29: 1237-124.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16kDa (monomer); 32kDa (homodimer)
NCBI Official Full Name
galactoside-binding soluble lectin 13
NCBI Official Synonym Full Names
galectin 13
NCBI Official Symbol
LGALS13
NCBI Official Synonym Symbols
PP13; GAL13; PLAC8
NCBI Protein Information
galactoside-binding soluble lectin 13
UniProt Protein Name
Galactoside-binding soluble lectin 13
UniProt Gene Name
LGALS13
UniProt Synonym Gene Names
PLAC8; Gal-13; PP13; Placental protein 13
Similar Products
Product Notes
The GAL13 lgals13 (Catalog #AAA214373) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Galectin-13 (GAL13)/Placental Protein 13 (PP13) reacts with Human. Others not known and may cross-react with other species as described in the data sheet. AAA Biotech's Galectin-13 (GAL13)/Placental Protein 13 (PP13) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the GAL13 lgals13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Galectin-13 (GAL13)/Placental Protein 13 (PP13), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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