Mouse anti-Human GCN5L2 Monoclonal Antibody | anti-GCN5L2 antibody

GCN5L2

Cat. Num. AAA48285

• Gene Names: KAT2A; GCN5; hGCN5; GCN5L2; PCAF-b
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: Protein-A Affinity Chromatography
• Synonyms: GCN5L2, Antibody; GCN5L2; KAT2A; general control of amino-acid synthesis 5-like 2; GCN5; PCAF-b; K(lysine) acetyltransferase 2A; hGCN5L2; anti-GCN5L2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2a kappa
• Clone Number: AT3G13
• Purity/Purification: Protein-A Affinity Chromatography
• Form/Format: Liquid; In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 837

• Applicable Applications for anti-GCN5L2 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Immunogen: Recombinant human GCN5L2 (411-837aa) purified from E Coli.
• Conjugation: Unconjugated
• Preparation and Storage: Can be stored at 2 degree C to 8 degree C for 1 week. For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.

WB (Western Blot)

(The cell lysate(35ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GCN5L2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;Lane 1.: HeLa cell lysate;)

ICC (Immunocytochemistry)

(ICC/IF analysis of GCN5L2 in HeLa cells. The cell was stained (1:500). The secondary antibody (green) was used Alexa Fluor 488.)

Related Product Information for anti-GCN5L2 antibody

GCN5L2, as known as GCN5 and KAT2A is the use of immunoprecipitated GCN5L2 for acetylation to provide the additional components important for acetylation. GCN5L2 can be one of the potential enzymes involved in acetylation in vivo. GCN5L2 is expressed predominantly in the embryo and newborn and is essential for normal embryonic development. Therefore, GCN5L2 appears to be important for differentiation of embryonic-derived preadipocytes. On the one hand, loss of GCN5L2 leads to high incidence of apoptosis in the GCN5L2 mutants that begins before the onset of morphological abnormality.

Product Categories/Family for anti-GCN5L2 antibody

Epigenetics and Nuclear Signaling

References

Wiper-Bergeron N, et al. (2007) Proc Natl Acad Sci U S A, 104(8):2703-8.;Jacob AL, et al. (2001) J Biol Chem, 276(40):37659-64. Xu W, et al. (2000) Nat Genet, 26(2):229-232.

NCBI and Uniprot Product Information

• NCBI GI #: 153791535
• NCBI GeneID: 2648
• NCBI Accession #: NP_066564.2
• NCBI GenBank Nucleotide #: NP_066564.2
• UniProt Accession #: Q92830
• NCBI Official Full Name: histone acetyltransferase KAT2A
• NCBI Official Synonym Full Names: lysine acetyltransferase 2A
• NCBI Official Symbol: KAT2A
• NCBI Official Synonym Symbols: GCN5; hGCN5; GCN5L2; PCAF-b
• NCBI Protein Information: histone acetyltransferase KAT2A
• UniProt Protein Name: Histone acetyltransferase KAT2A
• UniProt Gene Name: KAT2A
• UniProt Synonym Gene Names: GCN5; GCN5L2; HGCN5; HsGCN5
• UniProt Entry Name: KAT2A_HUMAN