FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of NIH/3T3 cells with Glucocorticoid Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
Rabbit Glucocorticoid Monoclonal Antibody | anti-NR3C1 antibody
Glucocorticoid Receptor Antibody
Gene Names
NR3C1; GR; GCR; GRL; GCCR
Reactivity
Human, Mouse, Rat, Zebrafish
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
ProA affinity purified
Synonyms
Glucocorticoid, Antibody; Glucocorticoid Receptor Antibody; GCCR antibody; GCR antibody; GCR_HUMAN antibody; GCRST antibody; glucocorticoid nuclear receptor variant 1 antibody; Glucocorticoid receptor antibody; GR antibody; GRL antibody; Grl1 antibody; nr3c1 antibody; Nuclear receptor subfamily 3 group C member 1 antibody; nuclear receptor subfamily 3; group C; member 1 (glucocorticoid receptor) antibody; anti-NR3C1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Clonality
Monoclonal
Clone Number
JF0952
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-NR3C1 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of NIH/3T3 cells with Glucocorticoid Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of NIH/3T3 cells with Glucocorticoid Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody)
WB (Western Blot)
(Western blot analysis of Glucocorticoid Receptor on hybrid fish (crucian-carp) heart tissue lysate using anti-Glucocorticoid Receptor antibody at 1/500 dilution.)
WB (Western Blot)
(Western blot analysis of Glucocorticoid Receptor on hybrid fish (crucian-carp) heart tissue lysate using anti-Glucocorticoid Receptor antibody at 1/500 dilution.)
WB (Western Blot)
(Western blot analysis of Glucocorticoid Receptor on different lysates using anti-Glucocorticoid Receptor antibody at 1/1, 000 dilution. Positive control: Lane 1: zebrafish Lane 2: A549 Lane 3: HepG2)
WB (Western Blot)
(Western blot analysis of Glucocorticoid Receptor on different lysates using anti-Glucocorticoid Receptor antibody at 1/1, 000 dilution. Positive control: Lane 1: zebrafish Lane 2: A549 Lane 3: HepG2)
Related Product Information for anti-NR3C1 antibody
The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR alpha. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.
Product Categories/Family for anti-NR3C1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
85,659 Da
NCBI Official Full Name
glucocorticoid receptor isoform alpha
NCBI Official Synonym Full Names
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NCBI Official Symbol
NR3C1
NCBI Official Synonym Symbols
GR; GCR; GRL; GCCR
NCBI Protein Information
glucocorticoid receptor; glucocorticoid nuclear receptor variant 1
UniProt Protein Name
Glucocorticoid receptor
UniProt Gene Name
NR3C1
UniProt Synonym Gene Names
GRL; GR
UniProt Entry Name
GCR_HUMAN
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Product Notes
The NR3C1 nr3c1 (Catalog #AAA312399) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glucocorticoid Receptor Antibody reacts with Human, Mouse, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's Glucocorticoid can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the NR3C1 nr3c1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glucocorticoid, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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