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product-image-AAA215683_IHC15.jpg IHC (Immunohistochemistry) (Formalin-fixed, paraffin-embedded human liver stained with Glutamine Synthetase Mouse Monoclonal Antibody (GLUL/6599) at 2ug/ml.)

Mouse anti-Human Glutamine Synthetase/GLUL Monoclonal Antibody | anti-GLUL antibody

Glutamine Synthetase/GLUL Mouse Monoclonal Antibody [Clone GLUL/6599]

Gene Names
GLUL; GS; GLNS; PIG43; PIG59
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Synonyms
Glutamine Synthetase/GLUL, Antibody; Glutamine Synthetase/GLUL Mouse Monoclonal Antibody [Clone GLUL/6599]; cell proliferation-inducing protein 59; GLUL; Glutamate ammonia ligase; GS; PIG43; PIG59; Glutamate decarboxylase; glutamine synthase; Glutamine synthetase; glutamine synthetase I; Proliferation inducing protein 43; GLNA; GLNS; anti-GLUL antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2b, kappa
Clone Number
GLUL/6599
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-GLUL antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant fragment (around aa 50-250) of human GLUL protein (exact sequence is proprietary)
Cellular Localization
Cytoplasm, Mitochondrion
Positive Control
Human brain, stomach or thyroid. A-431 or Y79 cells.
Hu-chromosome Location
1q25.3
Unigene
518525
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human liver stained with Glutamine Synthetase Mouse Monoclonal Antibody (GLUL/6599) at 2ug/ml.)

product-image-AAA215683_IHC15.jpg IHC (Immunohistochemistry) (Formalin-fixed, paraffin-embedded human liver stained with Glutamine Synthetase Mouse Monoclonal Antibody (GLUL/6599) at 2ug/ml.)
Related Product Information for anti-GLUL antibody
Glutamine synthetase (Gl Syn) forms a homo-octamer that serves as a catalyst for the amination of glutamic acid to form glutamine. This enzyme is a marker for astrocytes, which serve as the primary site of conversion of glutamic acid to glutamine in the brain. Induction of glutamine synthetase is seen upon astrocyte cell contact with neurons. Elevated expression of glutamine synthetase in glial cells has been shown to protect neurons from degeneration due to excess glutamate. Glutamine synthetase is also present in the liver and is involved in nitrogen homeostasis. Overexpression of glutamine synthetase has been shown in primary liver cancers, indicating a potential role for glutamine synthetase in hepatocyte transformation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,064 Da
NCBI Official Full Name
glutamine synthetase
NCBI Official Synonym Full Names
glutamate-ammonia ligase
NCBI Official Symbol
GLUL
NCBI Official Synonym Symbols
GS; GLNS; PIG43; PIG59
NCBI Protein Information
glutamine synthetase; glutamine synthase; glutamate decarboxylase; glutamate--ammonia ligase; proliferation-inducing protein 43; cell proliferation-inducing protein 59
UniProt Protein Name
Glutamine synthetase
UniProt Gene Name
GLUL
UniProt Synonym Gene Names
GLNS; GS
UniProt Entry Name
GLNA_HUMAN

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Product Notes

The GLUL glul (Catalog #AAA215683) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Glutamine Synthetase/GLUL Mouse Monoclonal Antibody [Clone GLUL/6599] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Glutamine Synthetase/GLUL can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GLUL glul for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutamine Synthetase/GLUL, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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