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product-image-AAA215440_AD8.jpg Application Data (Analysis of Protein Array containing more than 19,000 full-length human proteins using GM-CSF Mouse Monoclonal Antibody (CSF2/3403). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.)

Mouse anti-Human GM-CSF Monoclonal Antibody | anti-CSF2 antibody

GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor)

Gene Names
CSF2; CSF; GMCSF
Reactivity
Human
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
GM-CSF, Antibody; GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor); Burst Promoting Activity; Eosinophil Colony Stimulating Factor; Molgramostin; Pluripoietin Alpha; Sargramostim; anti-CSF2 antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b, kappa
Clone Number
CSF2/3403
Specificity
Granulocyte/macrophage - Colony-stimulating factor (GM-CSF) is a hematopoietic factor that is produced by activated T-cells, B-cells, mast cells, macrophages, fibroblasts, and endothelial cells. In addition to supporting colony formation of granulocyte/macrophage progenitors, GM-CSF is a growth factor for erythroid, megakaryocyte, and eosinophil progenitors.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
144
Applicable Applications for anti-CSF2 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant Human GM-CSF protein
Cellular Localization
Secreted (Extracellular)
Hu-chromosome Location
5q31.1
Positive Control
Human Spleen or Tonsil.
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Application Data

(Analysis of Protein Array containing more than 19,000 full-length human proteins using GM-CSF Mouse Monoclonal Antibody (CSF2/3403). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.)

product-image-AAA215440_AD8.jpg Application Data (Analysis of Protein Array containing more than 19,000 full-length human proteins using GM-CSF Mouse Monoclonal Antibody (CSF2/3403). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded human spleen stained with GM-CSF Mouse Monoclonal Antibody (CSF2/3403).)

product-image-AAA215440_IHC10.jpg IHC (Immunohistochemistry) (Formalin-fixed, paraffin-embedded human spleen stained with GM-CSF Mouse Monoclonal Antibody (CSF2/3403).)

IHC (Immunohistochemisry)

(Formalin-fixed, paraffin-embedded human spleen stained with GM-CSF Mouse Monoclonal Antibody (CSF2/3403).)

product-image-AAA215440_IHC11.jpg IHC (Immunohistochemisry) (Formalin-fixed, paraffin-embedded human spleen stained with GM-CSF Mouse Monoclonal Antibody (CSF2/3403).)

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded human spleen stained with GM-CSF Mouse Monoclonal Antibody (CSF2/3403).)

product-image-AAA215440_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed, paraffin-embedded human spleen stained with GM-CSF Mouse Monoclonal Antibody (CSF2/3403).)

SDS-PAGE

(SDS-PAGE Analysis Purified GM-CSF Mouse Monoclonal Antibody (CSF2/3403). Confirmation of Purity and Integrity of Antibody.)

product-image-AAA215440_SDS_PAGE15.jpg SDS-PAGE (SDS-PAGE Analysis Purified GM-CSF Mouse Monoclonal Antibody (CSF2/3403). Confirmation of Purity and Integrity of Antibody.)
References
Abrams J, et al. 1992. Immunol. Rev. 127:5. | Abrams J, et al. 1994. Eosinophils in Allergy and Inflammation. Marcel Dekker New York. p.133.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22kDa
NCBI Official Full Name
GM-CSF
NCBI Official Synonym Full Names
colony stimulating factor 2
NCBI Official Symbol
CSF2
NCBI Official Synonym Symbols
CSF; GMCSF
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor
UniProt Gene Name
CSF2
UniProt Synonym Gene Names
GMCSF; GM-CSF; CSF
UniProt Entry Name
CSF2_HUMAN

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Product Notes

The CSF2 csf2 (Catalog #AAA215440) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GM-CSF (Granulocyte/Macrophage - Colony Stimulating Factor) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GM-CSF can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CSF2 csf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GM-CSF, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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