ELISA
(Detects PcrV in indirect ELISAs.)
Gremubamab Monoclonal Antibody
Research Grade Gremubamab
Reactivity
P. aeruginosa
Purity
>95% by SDS-PAGE; Protein A or G purified from cell culture supernatant.
Synonyms
Gremubamab, Antibody; Research Grade Gremubamab; Bispecific; MEDI3902; Psl; PcrV; polysaccharide synthesis locus; surface exopolysaccharide; Type III secretion protein; Type III secretion protein PcrV; Virulence-associated V antigen; lcrV; anti-Gremubamab antibody
Reactivity
P. aeruginosa
Clonality
Monoclonal
Isotype
VH-CH1-VH-V-KAPPA-CH2-CH3
Clone Number
Gremubamab
Purity/Purification
>95% by SDS-PAGE; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. 0.01M PBS, pH 7.4
Concentration
2.54 mg/ml (varies by lot)
CAS
1800381-36-5
Host Species
Human/Humanized
Target
PcrV & Psl
Expression system
Mammalian Cells
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at -20 degree C for short term.
Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
ELISA
(Detects PcrV in indirect ELISAs.)
ELISA
(Detects PcrV in indirect ELISAs.)
SDS-PAGE
(SDS PAGE for Gremubamab)
SDS-PAGE
(SDS PAGE for Gremubamab)
Product Categories/Family for anti-Gremubamab antibody
References
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature, PMID: 28463232
MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model, PMID: 29483116
Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates, PMID: 30016475
Phase 1 study of MEDI3902, an investigational anti-Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults, PMID: 30107283
MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model, PMID: 29483116
Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates, PMID: 30016475
Phase 1 study of MEDI3902, an investigational anti-Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults, PMID: 30107283
NCBI and Uniprot Product Information
UniProt Accession #
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Product Notes
The Gremubamab (Catalog #AAA120154) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Gremubamab reacts with P. aeruginosa and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Gremubamab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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