Mouse Growth Hormone Monoclonal Antibody | anti-GH1 antibody

Growth Hormone (Pituitary Marker)

Cat. Num. AAA214748

• Gene Names: GH1; GH; GHN; GH-N; GHB5; hGH-N; IGHD1B
• Reactivity: Human. Others not known.
• Applications: Immunohistochemistry
• Purity: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Synonyms: Growth Hormone, Antibody; Growth Hormone (Pituitary Marker); GH; GH-N; GH1; GHN; Growth hormone 1; Growth hormone; Growth hormone, pituitary; HG1; hGH-N; IGHD1B; Pituitary growth hormone; RNGHGP; Somatotropin; anti-GH1 antibody

• Host: Mouse
• Reactivity: Human. Others not known.
• Clonality: Monoclonal
• Isotype: IgG1, kappa
• Clone Number: rGH/1450
• Specificity: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
• Purity/Purification: Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
• Form/Format: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Sequence Length: 202

• Applicable Applications for anti-GH1 antibody: IHC (Immunohistochemistry)
• Immunogen: A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)
• Positive Control: Pituitary Cells or Pituitary
• Cellular Localization: Cytoplasmic
• Chromosome Location: 17q24.2
• Preparation and Storage: Antibody with azide - store at 2 to 8 degree C.; Antibody without azide - store at -20 to -80 degree C.; Antibody is stable for 24 months. Non-hazardous. No MSDS required.

SDS-PAGE

(SDS-PAGE Analysis Purified Growth Hormone Recombinant Mouse Monoclonal (rGH/1450). Confirmation of Purity and Integrity of Antibody.)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded Human Pituitary stained with Growth Hormone Recombinant Mouse Monoclonal Antibody (rGH/1450).)

Related Product Information for anti-GH1 antibody

Recombinant Mouse Monoclonal Antibody

References

Niall, H.D., et al. 1971. Sequence of pituitary and placental lactogenic and growth hormones: evolution from a primordial peptide by gene reduplication. Proc. Natl. Acad. Sci. USA 68: 866-869.

NCBI and Uniprot Product Information

• NCBI GI #: 13027812
• NCBI GeneID: 2688
• NCBI Accession #: NP_000506.2
• NCBI GenBank Nucleotide #: NM_000515.4
• UniProt Accession #: P01241; Q14405; Q16631; Q5EB53; Q9HBZ1; Q9UMJ7; Q9UNL5; A6NEF6
• Molecular Weight: 20kDa
• NCBI Official Full Name: somatotropin isoform 1
• NCBI Official Synonym Full Names: growth hormone 1
• NCBI Official Symbol: GH1
• NCBI Official Synonym Symbols: GH; GHN; GH-N; GHB5; hGH-N; IGHD1B
• NCBI Protein Information: somatotropin
• UniProt Protein Name: Somatotropin
• UniProt Gene Name: GH1
• UniProt Synonym Gene Names: GH; GH-N