Application Data
Mouse GSDMD Monoclonal Antibody | anti-GSDMD antibody
GSDMD antibody
Gene Names
GSDMD; DF5L; DFNA5L; FKSG10; GSDMDC1
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
>=95% as determined by SDS-PAGEProtein A+G purification
Synonyms
GSDMD, Antibody; GSDMD antibody; DF5L; DFNA5L; FKSG10; FLJ12150; gasdermin D; GSDMD; GSDMDC1; anti-GSDMD antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
10D7
Purity/Purification
>=95% as determined by SDS-PAGE
Protein A+G purification
Protein A+G purification
Form/Format
Liquid
Applicable Applications for anti-GSDMD antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Immunogen
gasdermin D
Research Area
Developmental biology
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 12 months(Avoid repeated freeze / thaw cycles.)
Application Data
Application Data
IF (Immunofluorescence)
(Immunofluorescent analysis of Hela cells using AAA251234 (GSDMD antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-mouse IgG(H+L))
IF (Immunofluorescence)
(Immunofluorescent analysis of Hela cells using AAA251234 (GSDMD antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-mouse IgG(H+L))
Related Product Information for anti-GSDMD antibody
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1beta secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Product Categories/Family for anti-GSDMD antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,801 Da
NCBI Official Full Name
gasdermin-D
NCBI Official Synonym Full Names
gasdermin D
NCBI Official Symbol
GSDMD
NCBI Official Synonym Symbols
DF5L; DFNA5L; FKSG10; GSDMDC1
NCBI Protein Information
gasdermin-D; gasdermin domain containing 1; gasdermin domain-containing protein 1
UniProt Protein Name
Gasdermin-D
UniProt Gene Name
GSDMD
UniProt Synonym Gene Names
DFNA5L; GSDMDC1
UniProt Entry Name
GSDMD_HUMAN
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Product Notes
The GSDMD gsdmd (Catalog #AAA251234) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GSDMD antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GSDMD can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the GSDMD gsdmd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GSDMD, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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