Rabbit anti-Human GSTM2 Monoclonal Antibody | anti-GSTM2 antibody

Recombinant Anti-GSTM2 Antibody, Rabbit Monoclonal

Cat. Num. AAA255504

• Gene Names: GSTM2; GST4; GSTM; GTHMUS; GSTM2-2
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Protein A
• Synonyms: GSTM2, Antibody; Recombinant Anti-GSTM2 Antibody, Rabbit Monoclonal; GSTM2 Antibody, Rabbit MAb; glutathione S-transferase mu 2 (muscle); Anti-GST4 Antibody; Anti-GSTM Antibody; Anti-GSTM2-2 Antibody; Anti-GTHMUS Antibody; anti-GSTM2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone Number: 005
• Specificity: Human GSTM2
• Purity/Purification: Protein A
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-GSTM2 antibody: IHC (Immunohistochemistry)
• Antibody Type: Recombinant Antibody
• Immunogen: Recombinant Human GSTM2 protein
• Conjugation: Unconjugated
• Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human GSTM2 (rh GSTM2).
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohistochemisry)

(Immunochemical staining of human GSTM2 in human epididymis with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).Positive staining was localized to skeletal muscle.)

IHC (Immunohiostchemistry)

(Immunochemical staining of human GSTM2 in human heart with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)

IHC (Immunohistochemistry)

(Immunochemical staining of human GSTM2 in human leiomyoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).)

Related Product Information for anti-GSTM2 antibody

Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2, and GSTM2, is a cytoplasm protein that belongs to the GST superfamily and Mu family. GSTM2/GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta. Butyrate, an important luminal component produced from the fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotective by increasing detoxification capabilities in the colon mucosa.

References

Campbell E, et al., 1990, J Biol Chem 265 (16): 9188-93. Vorachek WR, et al., 1991, Proc Natl Acad Sci USA. 88 (10): 4443-7. Ebert, M.N. et al., 2003, Carcinogenesis. 24 (10):1637-44.

NCBI and Uniprot Product Information

• NCBI GI #: 215277000
• NCBI GeneID: 2946
• NCBI Accession #: NP_001135840.1
• NCBI GenBank Nucleotide #: NM_001142368.1
• UniProt Accession #: P28161; Q2M318; Q5TZY5; Q8WWE1; B4DRY4; E9PEM9
• Molecular Weight: 25,745 Da
• NCBI Official Full Name: glutathione S-transferase Mu 2 isoform 2
• NCBI Official Synonym Full Names: glutathione S-transferase mu 2 (muscle)
• NCBI Official Symbol: GSTM2
• NCBI Official Synonym Symbols: GST4; GSTM; GTHMUS; GSTM2-2
• NCBI Protein Information: glutathione S-transferase Mu 2; GST, muscle; GST class-mu 2; glutathione S-transferase 4; glutathione S-transferase M1; glutathione S-aryltransferase M2; glutathione S-alkyltransferase M2; glutathione S-aralkyltransferase M2; S-(hydroxyalkyl)glutathione l
• UniProt Protein Name: Glutathione S-transferase Mu 2
• UniProt Gene Name: GSTM2
• UniProt Synonym Gene Names: GST4
• UniProt Entry Name: GSTM2_HUMAN