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ICC (Immunocytochemistry)
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Rabbit hnRNP Q Monoclonal Antibody | anti-SYNCRIP antibody

hnRNP Q Antibody

Gene Names
SYNCRIP; PP68; NSAP1; GRYRBP; HNRNPQ; HNRPQ1; GRY-RBP; hnRNP-Q
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Purity
ProA affinity purified
Synonyms
hnRNP Q, Antibody; hnRNP Q Antibody; cytoplasmic RNA-interacting protein antibody; dJ3J17.2 antibody; Glycine and tyrosine rich RNA binding protein antibody; Glycine- and tyrosine-rich RNA-binding protein antibody; GRY RBP antibody; GRY-RBP antibody; GRYRBP antibody; Heterogeneous nuclear ribonucleoprotein Q antibody; hnRNP Q antibody; HNRPQ antibody; HNRPQ_HUMAN antibody; HNRPQ1 antibody; NS1 associated protein 1 antibody; NS1-associated protein 1 antibody; NSAP1 antibody; pp68 antibody; RP1 3J17.2 antibody; Synaptotagmin binding cytoplasmic RNA interacting protein antibody; Synaptotagmin-binding antibody; Syncrip antibody; anti-SYNCRIP antibody
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For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
JG35-72
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-SYNCRIP antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF),Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC: 1:50-1:200
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein to C-terminal human hnRNP Q.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

ICC (Immunocytochemistry)

(ICC staining hnRNP Q in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining hnRNP Q in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human thyroid gland tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded rat testis tissue using anti-hnRNP Q antibody. Counter stained with hematoxylin.)

WB (Western Blot)

(Western blot analysis of hnRNP Q on K562 cell lysate using anti-hnRNP Q antibody at 1/1, 000 dilution.)

Related Product Information for anti-SYNCRIP antibody
Pre-mRNA splicing is a critical step in the posttranscriptional regulation of gene expression. Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) is involved in RNA processing and is necessary for efficient pre-mRNA splicing. hnRNP is widely expressed and developmentally regulated. hnRNP Q interacts with survival motor neuron protein (SMN). Loss of function of SMN results in spinal muscular atrophy, a common neurodegenerative disease. The most common deletion in SMN genes disrupts the interaction between SMN and hnRNP Q. hnRNP Q is upregulated after midnight, and this upregulation correlates with an abrupt decline in AANAT, the key enzyme in melatonin synthesis. Rhythmic AANAT mRNA degradation mediated in part by hnRNP Q implicates this enzyme in the regulation of circadian oscillation.
Product Categories/Family for anti-SYNCRIP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69,603 Da
NCBI Official Full Name
heterogeneous nuclear ribonucleoprotein Q isoform 2
NCBI Official Synonym Full Names
synaptotagmin binding, cytoplasmic RNA interacting protein
NCBI Official Symbol
SYNCRIP
NCBI Official Synonym Symbols
PP68; NSAP1; GRYRBP; HNRNPQ; HNRPQ1; GRY-RBP; hnRNP-Q
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein Q; NS1-associated protein 1; glycine- and tyrosine-rich RNA-binding protein
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein Q
UniProt Gene Name
SYNCRIP
UniProt Synonym Gene Names
HNRPQ; NSAP1; hnRNP Q; GRY-RBP
UniProt Entry Name
HNRPQ_HUMAN

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Product Notes

The SYNCRIP syncrip (Catalog #AAA30484) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The hnRNP Q Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's hnRNP Q can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF),Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200 ICC: 1:50-1:200. Researchers should empirically determine the suitability of the SYNCRIP syncrip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hnRNP Q, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.