IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using hnRNP Q antibody.)
Rabbit hnRNP Q Polyclonal Antibody | anti-hnRNP Q antibody
hnRNP Q Antibody
Gene Names
SYNCRIP; PP68; NSAP1; GRYRBP; HNRNPQ; HNRPQ1; GRY-RBP; hnRNP-Q
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
hnRNP Q, Antibody; hnRNP Q Antibody; Heterogeneous nuclear ribonucleoprotein Q; hnRNP Q; hnRNP-Q; Synaptotagmin-binding; cytoplasmic RNA-interacting protein; anti-hnRNP Q antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total hnRNP Q protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
464
Applicable Applications for anti-hnRNP Q antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from Internal of human hnRNP Q.
Target Name
hnRNP Q
Preparation and Storage
Store at -20 degree C
IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using hnRNP Q antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using hnRNP Q antibody.)
WB (Western Blot)
(Western blot analysis of extracts from HUVEC cells, Jurkat cells and 293 cells, using hnRNP Q antibody.)
WB (Western Blot)
(Western blot analysis of extracts from HUVEC cells, Jurkat cells and 293 cells, using hnRNP Q antibody.)
Related Product Information for anti-hnRNP Q antibody
Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation; seems not to be essential for GAIT complex function.Harris C.E., J. Virol. 73:72-80(1999).Du G., Chin. Sci. Bull. 45:343-349(2000).Mourelatos Z., EMBO J. 20:5443-5452(2001).
Product Categories/Family for anti-hnRNP Q antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,328 Da
NCBI Official Full Name
heterogeneous nuclear ribonucleoprotein Q isoform 2
NCBI Official Synonym Full Names
synaptotagmin binding, cytoplasmic RNA interacting protein
NCBI Official Symbol
SYNCRIP
NCBI Official Synonym Symbols
PP68; NSAP1; GRYRBP; HNRNPQ; HNRPQ1; GRY-RBP; hnRNP-Q
NCBI Protein Information
heterogeneous nuclear ribonucleoprotein Q
UniProt Protein Name
Heterogeneous nuclear ribonucleoprotein Q
UniProt Gene Name
SYNCRIP
UniProt Synonym Gene Names
HNRPQ; NSAP1; hnRNP Q; GRY-RBP
UniProt Entry Name
HNRPQ_HUMAN
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Product Notes
The hnRNP Q syncrip (Catalog #AAA305358) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The hnRNP Q Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's hnRNP Q can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the hnRNP Q syncrip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hnRNP Q, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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