WB (Western Blot)
(HeLa cells were subjected to SDS PAGE followed by western blot with AAA247946 (IFITM3 antibody) at dilution of 1:1000)
Mouse anti-Human IFITM3 Monoclonal Antibody | anti-IFITM3 antibody
IFITM3 Mouse Monoclonal
Gene Names
IFITM3; 1-8U; IP15; DSPA2b
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
>95% as determined by SDS-PAGEProtein A+G purification
Synonyms
IFITM3, Antibody; IFITM3 Mouse Monoclonal; 1 8U, IFITM3 , IP15; anti-IFITM3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5H4
Purity/Purification
>95% as determined by SDS-PAGE
Protein A+G purification
Protein A+G purification
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3,
Sequence Length
133
Applicable Applications for anti-IFITM3 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), IF (Immunofluorescence), WB (Western Blot), ELISA
Immunogen
IFITM2/3 fusion protein.
Preparation and Storage
Store at -20 degree C for 12 months (Avoid repeated freeze / thaw cycles.)
WB (Western Blot)
(HeLa cells were subjected to SDS PAGE followed by western blot with AAA247946 (IFITM3 antibody) at dilution of 1:1000)
WB (Western Blot)
(HeLa cells were subjected to SDS PAGE followed by western blot with AAA247946 (IFITM3 antibody) at dilution of 1:1000)
IF (Immunofluorescence)
(Immunofluorescent analysis of HepG2 cells, using IFITM3 antibody AAA247946 at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red))
IF (Immunofluorescence)
(Immunofluorescent analysis of HepG2 cells, using IFITM3 antibody AAA247946 at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human lung cancer using AAA247946 (IFITM3 antibody) at dilution of 1:50)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human lung cancer using AAA247946 (IFITM3 antibody) at dilution of 1:50)
Related Product Information for anti-IFITM3 antibody
IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis.Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell,by letting them go out with a cholesterol depleted membrane.Active against multiple viruses, including influenza A virus, SARS coronavirus(SARS-CoV).Marbug virus(MARV) and Ebola virus(EBOV),Dengue virus(DNV),West Nile virus(WNV),human immunodeficiency virus type 1(HIV-1) and vesicular stomatitis virus (VSV).Can inhibit influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase(v-ATPase).Establiches physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lowew the pH in phagocytic endosomes thus establishing an antiviral state. This antibody recognizes both IFITM2 and IFTIM3.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Observed MW: 14 kDa
NCBI Official Full Name
IFITM3
NCBI Official Synonym Full Names
interferon induced transmembrane protein 3
NCBI Official Symbol
IFITM3
NCBI Official Synonym Symbols
1-8U; IP15; DSPA2b
NCBI Protein Information
interferon-induced transmembrane protein 3
UniProt Protein Name
Interferon-induced transmembrane protein 3
UniProt Gene Name
IFITM3
UniProt Synonym Gene Names
DSPA2b
UniProt Entry Name
IFM3_HUMAN
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Product Notes
The IFITM3 ifitm3 (Catalog #AAA247946) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IFITM3 Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IFITM3 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IFITM3 ifitm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IFITM3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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