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ICC (Immunocytochemistry)
(ICC staining IKBKE in SK-Br-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Rabbit anti-Human IKBKE Monoclonal Antibody | anti-IKBKE antibody
IKBKE Antibody
Gene Names
IKBKE; IKKE; IKKI; IKK-E; IKK-i
Reactivity
Human
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
IKBKE, Antibody; IKBKE Antibody; I kappa B kinase epsilon antibody; I-kappa-B kinase epsilon antibody; IkBKE antibody; IKK related kinase epsilon antibody; IKK-E antibody; IKK-epsilon antibody; IKK-i antibody; IKKE antibody; IKKE_HUMAN antibody; IKKepsilon antibody; IKKI antibody; Inducible I kappa B kinase antibody; Inducible I kappa-B kinase antibody; Inducible IkappaB kinase antibody; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon antibody; Inhibitor of kappa light polypeptide gene enhancer in B cells; kinase of; epsilon antibody; Inhibitor of nuclear factor kappa-B kinase subunit epsilon antibody; KIAA0151 antibody; MGC125294 antibody; MGC125295 antibody; MGC125297 antibody; anti-IKBKE antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Clone Number
JU06-72
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-IKBKE antibody
IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
ICC (Immunocytochemistry)
(ICC staining IKBKE in SK-Br-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining IKBKE in SK-Br-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining IKBKE in JAR cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining IKBKE in JAR cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining IKBKE in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining IKBKE in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IKBKE antibody. Counter stained with hematoxylin.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IKBKE antibody. Counter stained with hematoxylin.)
WB (Western Blot)
(Western blot analysis of IKBKE on different cell lysates using anti-IKBKE antibody at 1/500 dilution. Positive control: Lane 1: Hela Lane 2: Raji Lane 3: MCF-7 Lane 4: Jurkat)
WB (Western Blot)
(Western blot analysis of IKBKE on different cell lysates using anti-IKBKE antibody at 1/500 dilution. Positive control: Lane 1: Hela Lane 2: Raji Lane 3: MCF-7 Lane 4: Jurkat)
Related Product Information for anti-IKBKE antibody
The transcription factor NFkappaB is retained in the cytoplasm in an inactive form by the inhibitory protein IkappaB. Activation of NFkappaB requires that IkappaB be phosphorylated on specific serine residues, which results in targeted degradation of IkappaB. IkappaB kinase alpha (IKKalpha), previously designated CHUK, interacts with IkappaB-alpha and specifically phosphorylates IkappaB-alpha on the sites that trigger its degradation, Serines 32 and 36. The functional IKK complex contains three subunits, IKKalpha, IKKbeta and IKKgamma (also designated NEMO), and each appear to make essential contributions to IkappaB phosphorylation. IKK-i is a serine/threonine kinase that shares homology with IKKalpha and IKKbeta . IKK-i is primarily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNFalpha, IL-1 and IL-6. Overexpression of IKK-i has been shown to result in phosphorylation of IkappaBalpha on Ser 32 and Ser 36, and in NFkappaB activation, suggesting that IKK-i may act as an IkappaB kinase in the immune system.
Product Categories/Family for anti-IKBKE antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
716
NCBI Official Full Name
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
NCBI Official Synonym Full Names
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
NCBI Official Symbol
IKBKE
NCBI Official Synonym Symbols
IKKE; IKKI; IKK-E; IKK-i
NCBI Protein Information
inhibitor of nuclear factor kappa-B kinase subunit epsilon; IKK-epsilon; I-kappa-B kinase epsilon; inducible IkappaB kinase; IKK-related kinase epsilon; inducible I kappa-B kinase
UniProt Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
UniProt Gene Name
IKBKE
UniProt Synonym Gene Names
IKKE; IKKI; KIAA0151; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; IKK-i
UniProt Entry Name
IKKE_HUMAN
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Product Notes
The IKBKE ikbke (Catalog #AAA312566) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IKBKE Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IKBKE can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the IKBKE ikbke for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKBKE, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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