ELISA
(Standard curve generated with Mouse Anti-Human IL-31-UNLB and Mouse Anti-Human IL-31-BIOT (AAA78625 Clone # SB118b))
Mouse anti-Human IL-31 Monoclonal Antibody | anti-IL31 antibody
Mouse Anti-Human IL-31-BIOT
Gene Names
IL31; IL-31
Reactivity
Human
Applications
ELISA
Synonyms
IL-31, Antibody; Mouse Anti-Human IL-31-BIOT; Mouse anti-Human Interleukin-31 (IL-31); anti-IL31 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
SB118b1
Specificity
Reacts with native and recombinant human IL-311
Form/Format
Biotin (BIOT) Conjugate
Applicable Applications for anti-IL31 antibody
ELISA
Immunogen
Recombinant human IL-31
Characterization
To ensure acceptable performance, each batch of product is tested by ELISA to conform to characteristics of a standard reference reagent.
Preparation and Storage
The biotin (BIOT) conjugate is supplied as 0.5mg labeled antibody in 0.2mL of PBS/NaN3. Store at 2-8 degree C.
ELISA
(Standard curve generated with Mouse Anti-Human IL-31-UNLB and Mouse Anti-Human IL-31-BIOT (AAA78625 Clone # SB118b))
ELISA
(Standard curve generated with Mouse Anti-Human IL-31-UNLB and Mouse Anti-Human IL-31-BIOT (AAA78625 Clone # SB118b))
Related Product Information for anti-IL31 antibody
Description: Interleukin-31 (IL-31) is a 24kD alpha-helical protein and a member of the IL-6 family of cytokines that is preferentially expressed by CD4+ T cells (2). This cytokine elicits its response by binding to a heterodimeric complex consisting of a gp130-like receptor chain and the oncostatin M receptor subunit. On target cells which include a broad range of immune and non-immune cells, IL-31 binding can induce activation of the Jak/STAT, AKT and MAPK signaling pathways. Due to the ubiquitous expression of its receptor complex, IL-31 has numerous physiological roles that include regulating hematopoiesis and immune response (3,4). Over-expression has been linked chronic inflammatory states such as dermatitis, pruritus, airway hypersensitivity and inflammatory bowel disease5-7.
References
1) Zhang, Q. et al. (2008). Cyto. Grow. Rev. 19:347-56.
3) Broxmeyer, H.E. et al. (2007). Exp. Hematol. 35:78-86.
4) Perrigoue, J.G. et al. (2007). J. Exp. Med. 204:481-7.
5) Sonkoly, E. et al. (2006). J. All. Clin. Immunol. 117:411-7.
6) Dillon, S.R. et al. (2004). Nat. Immunol. 5:752-60.
7) Dambacher, J. et al. (2007). Gut. 56:1257-65.
3) Broxmeyer, H.E. et al. (2007). Exp. Hematol. 35:78-86.
4) Perrigoue, J.G. et al. (2007). J. Exp. Med. 204:481-7.
5) Sonkoly, E. et al. (2006). J. All. Clin. Immunol. 117:411-7.
6) Dillon, S.R. et al. (2004). Nat. Immunol. 5:752-60.
7) Dambacher, J. et al. (2007). Gut. 56:1257-65.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
interleukin-31
NCBI Official Synonym Full Names
interleukin 31
NCBI Official Symbol
IL31
NCBI Official Synonym Symbols
IL-31
NCBI Protein Information
interleukin-31
UniProt Protein Name
Interleukin-31
UniProt Gene Name
IL31
UniProt Synonym Gene Names
IL-31
UniProt Entry Name
IL31_HUMAN
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Product Notes
The IL31 il31 (Catalog #AAA78625) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human IL-31-BIOT reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL-31 can be used in a range of immunoassay formats including, but not limited to, ELISA. Researchers should empirically determine the suitability of the IL31 il31 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-31, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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