IL-33 recombinant antibody

Recombinant Anti-IL-33 Antibody, Rabbit Monoclonal

Cat. Num. AAA258796

• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Protein A
• Synonyms: IL-33, Recombinant Antibody; Recombinant Anti-IL-33 Antibody, Rabbit Monoclonal; interleukin 33; Anti-C9orf26 Antibody; Anti-DVS27 Antibody; Anti-IL1F11 Antibody; Anti-NF-HEV Antibody; Anti-NFEHEV Antibody; IL-33 recombinant antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: Rabbit IgG
• Clone Number: #742
• Specificity: Human IL-33
• Purity/Purification: Protein A
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for IL-33 recombinant antibody: IHC (Immunohistochemistry), ELISA
• Immunogen: Recombinant Human IL-33 Protein
• Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Human IL-33 (rh IL-33).
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohiostchemistry)

(Immunochemical staining of human IL-33 in human tonsil with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)

IHC (Immunohistochemistry)

(Immunochemical staining of human IL-33 in human stomach with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)

Related Product Information for IL-33 recombinant antibody

Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.

References

Iikura M, et al. (2007) IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest. 87(10): 971-8.Lamkanfi M, et al. (2009) IL-33 raises alarm. Immunity. 31(1): 5-7.