IHC (Immunohiostchemistry)
(IL10RA Antibody-Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.)
Mouse anti-Human IL10RA Monoclonal Antibody | anti-IL10RA antibody
IL10RA Mouse anti-Human Monoclonal (1D10) Antibody
Gene Names
IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
IL10RA, Antibody; IL10RA Mouse anti-Human Monoclonal (1D10) Antibody; PathPlus IL10RA Antibody (clone 1D10); IL10RA; CD210; CD210a; CD210 antigen; IBD28; IL-10R subunit 1; Il-10r; IL-10R subunit alpha; Interleukin 10 receptor; alpha; IL10R; Interleukin-10 receptor; HIL-10R; CDW210A; IL-10 receptor subunit alpha; IL-10R1; IL-10RA; Interleukin-10 receptors; IL-10 RA; anti-IL10RA antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1D10
Specificity
Human IL10RA
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, pH7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-IL10RA antibody
WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target
Human IL10RA
Immunogen
Full length human recombinant protein of human IL10RA(NP_001549) produced in HEK293T cell.
Conjugation
Unconjugated
Family
Interleukin
Preparation and Storage
Store at -20 degree C. Avoid freeze-thaw cycles.
IHC (Immunohiostchemistry)
(IL10RA Antibody-Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.)
IHC (Immunohiostchemistry)
(IL10RA Antibody-Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.)
WB (Western Blot)
(IL10RA Antibody-HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL10RA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL10RA. At a dilution of 1:4000.)
WB (Western Blot)
(IL10RA Antibody-HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL10RA (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL10RA. At a dilution of 1:4000.)
Related Product Information for anti-IL10RA antibody
IL10RA antibody is an unconjugated mouse monoclonal antibody to human IL10RA. Validated for IHC and WB.
IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
IL10RA is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
References
The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,003 Da
NCBI Official Full Name
interleukin-10 receptor subunit alpha
NCBI Official Synonym Full Names
interleukin 10 receptor, alpha
NCBI Official Symbol
IL10RA
NCBI Official Synonym Symbols
CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
NCBI Protein Information
interleukin-10 receptor subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R subunit alpha; IL-10 receptor subunit alpha; interleukin-10 receptor subunit 1; interleukin-10 receptor alpha chain
UniProt Protein Name
Interleukin-10 receptor subunit alpha
UniProt Gene Name
IL10RA
UniProt Synonym Gene Names
IL10R; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R1
UniProt Entry Name
I10R1_HUMAN
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Product Notes
The IL10RA il10ra (Catalog #AAA162853) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IL10RA Mouse anti-Human Monoclonal (1D10) Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL10RA can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IL10RA il10ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL10RA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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