SDS-PAGE
(SDS PAGE for Inclacumab)
Inclacumab Monoclonal Antibody | anti-SELP antibody
Research Grade Inclacumab
Gene Names
SELP; CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
Reactivity
Homo sapiens (Human)
Purity
>95% by SDS-PAGE. Protein A or G purified from cell culture supernatant.
Synonyms
Inclacumab, Antibody; Research Grade Inclacumab; LC1004-002; RO4905417; Leukocyte-endothelial cell adhesion molecule 3; Platelet activation dependent granule-external membrane protein; Granule membrane protein 140; GMP-140; CD62P; SELP; GRMP; PADGEM; CD62 antigen-like family member P; LECAM3; P-selectin; GMRP; anti-SELP antibody
Reactivity
Homo sapiens (Human)
Clonality
Monoclonal
Isotype
IgG4-kappa
Purity/Purification
>95% by SDS-PAGE. Protein A or G purified from cell culture supernatant.
Form/Format
Liquid; 0.01M PBS, pH 7.4
Concentration
1.68 mg/ml (varies by lot)
Expression System
XtenCHO
Host Species
Human
Target
Leukocyte-endothelial cell adhesion molecule 3, Platelet activation dependent granule-external membrane protein, Granule membrane protein 140, GMP-140, CD62P, SELP, GRMP, PADGEM, CD62 antigen-like family member P, LECAM3, P-selectin, GMRPCAS
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4°C for short term (1-2 weeks).
Store at -20°C for 12 months.
Store at -80°C for long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at -20°C for 12 months.
Store at -80°C for long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Inclacumab)
SDS-PAGE
(SDS PAGE for Inclacumab)
Product Categories/Family for anti-SELP antibody
References
First-in-Man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin, PMID: 25714598
Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT-ACS Trial, PMID: 27852589
Lack of ethnic differences in the pharmacokinetics and pharmacodynamics of inclacumab in healthy Japanese and Caucasian subjects, PMID: 26363899
Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab--preclinical and clinical studies, PMID: 23522853
Effects of the P-selectin antagonist inclacumab on myocardial damage after percutaneous coronary intervention for non-ST-segment elevation myocardial infarction: results of the SELECT-ACS trial, PMID: 23500230
Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT-ACS Trial, PMID: 27852589
Lack of ethnic differences in the pharmacokinetics and pharmacodynamics of inclacumab in healthy Japanese and Caucasian subjects, PMID: 26363899
Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab--preclinical and clinical studies, PMID: 23522853
Effects of the P-selectin antagonist inclacumab on myocardial damage after percutaneous coronary intervention for non-ST-segment elevation myocardial infarction: results of the SELECT-ACS trial, PMID: 23500230
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
granule membrane protein-140
NCBI Official Synonym Full Names
selectin P (granule membrane protein 140kDa, antigen CD62)
NCBI Official Symbol
SELP
NCBI Official Synonym Symbols
CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
NCBI Protein Information
P-selectin; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external mem
UniProt Protein Name
P-selectin
UniProt Gene Name
SELP
UniProt Synonym Gene Names
GMRP; GRMP; GMP-140; LECAM3; PADGEM
UniProt Entry Name
LYAM3_HUMAN
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Product Notes
The SELP selp (Catalog #AAA120048) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Inclacumab reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Inclacumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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