SDS-PAGE
(SDS-PAGE Analysis Purified IGF-1 Mouse Monoclonal Antibody (M23). Confirmation of Purity and Integrity of Antibody.)
Mouse Insulin-like Growth Factor-1 Monoclonal Antibody | anti-IGF1 antibody
Insulin-like Growth Factor-1 (IGF-1)
Gene Names
IGF1; IGFI; IGF-I; IGF1A
Reactivity
Human, Mouse, Rat, Rabbit.
Applications
Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
Insulin-like Growth Factor-1, Antibody; Insulin-like Growth Factor-1 (IGF-1); Insulin-like Growth Factor IA (IGF-IA); Insulin-like Growth Factor IB (IGF-IB); Mechano Growth Factor (MGF); Somatomedin-C; anti-IGF1 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat, Rabbit.
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
M23
Specificity
This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
153
Applicable Applications for anti-IGF1 antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Localization
Cytoplasmic (Secreted)
Positive Control
Pancreas or brain. Breast, Thyroid or Colon Cancers; IGF-1 recombinant protein
Human Chromosomal Location
12q23.2
Immunogen
Purified human IGF-1 protein
Quantity and Buffer
0.5 ml at 200ug/ml with BSA and azide
Preparation and Storage
Store at 2 to 8 degree C. Antibody is stable for 24 months.
SDS-PAGE
(SDS-PAGE Analysis Purified IGF-1 Mouse Monoclonal Antibody (M23). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified IGF-1 Mouse Monoclonal Antibody (M23). Confirmation of Purity and Integrity of Antibody.)
References
1. Rotwein p, et. al. (1986) J. Biol. Chem. 261: 4828-4832.
2. Sandberg-Nordqvist AC, et. al. (1993) Cancer Res. 53: 2475-2478.
3. Zheng WH, et. al. (2000) J. Neural.Transm. Suppl. 2000: 261-272.
2. Sandberg-Nordqvist AC, et. al. (1993) Cancer Res. 53: 2475-2478.
3. Zheng WH, et. al. (2000) J. Neural.Transm. Suppl. 2000: 261-272.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~7.6kDa
NCBI Official Full Name
insulin-like growth factor I isoform 4 preproprotein
NCBI Official Synonym Full Names
insulin-like growth factor 1 (somatomedin C)
NCBI Official Symbol
IGF1
NCBI Official Synonym Symbols
IGFI; IGF-I; IGF1A
NCBI Protein Information
insulin-like growth factor I; MGF; IGF-IA; IGF-IB; somatomedin-C; mechano growth factor; insulin-like growth factor IA; insulin-like growth factor IB
UniProt Protein Name
Insulin-like growth factor I
UniProt Gene Name
Igf1
UniProt Synonym Gene Names
Igf-1; IGF-I
UniProt Entry Name
IGF1_MOUSE
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Product Notes
The IGF1 igf1 (Catalog #AAA62663) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Insulin-like Growth Factor-1 (IGF-1) reacts with Human, Mouse, Rat, Rabbit. and may cross-react with other species as described in the data sheet. AAA Biotech's Insulin-like Growth Factor-1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the IGF1 igf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Insulin-like Growth Factor-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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