SDS-PAGE
(SDS-PAGE Analysis Purified Interleukin-3 (IL-3) Mouse Monoclonal Antibody (IL3/4005). Confirmation of Purity and Integrity of Antibody.)
Mouse anti-Human Interleukin-3 (IL-3) Monoclonal Antibody | anti-IL3 antibody
Interleukin-3 (IL-3) Mouse Monoclonal Antibody [Clone IL3/4005]
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Interleukin-3 (IL-3), Antibody; Interleukin-3 (IL-3) Mouse Monoclonal Antibody [Clone IL3/4005]; Colony stimulating factor multiple; Hematopoietic growth factor; Interleukin 3 (colony stimulating factor, multiple); Mast cell growth factor; MCGF; Multi CSF; Multilineage colony stimulating factor; P cell stimulating factor; anti-IL3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG2b, kappa
Clone Number
IL3/4005
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-IL3 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment of human IL3 protein (exact sequence is proprietary)
Cellular Localization
Secreted
Positive Control
Human thymus or tonsil tissue.
Hu-chromosome Location
5q31.1
Unigene
694
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified Interleukin-3 (IL-3) Mouse Monoclonal Antibody (IL3/4005). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified Interleukin-3 (IL-3) Mouse Monoclonal Antibody (IL3/4005). Confirmation of Purity and Integrity of Antibody.)
Related Product Information for anti-IL3 antibody
Interleukin-3, or IL-3, is a pleiotropic cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL-3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL-3 has also been shown to protect mast cells from undergoing apoptosis. IL-3 exerts its biological effects through a receptor which consists of a ligand-specific alpha subunit and a signal transducing beta subunit common to the IL-3/IL-5/GM-CSF receptors. The carboxy terminus of the beta subunit has been shown to be necessary for activation of the MAP kinase signaling pathway. Although the IL-3 receptor has no intrinsic kinase activity, stimulation with IL-3 leads to tyrosine phosphorylation of the JAK/Tyk 2 family member, JAK2, which in turn activates and causes nuclear translocation of Stat5a and Stat5b.
NCBI and Uniprot Product Information
NCBI GeneID
Molecular Weight
17kDa
Similar Products
Product Notes
The IL3 (Catalog #AAA215740) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Interleukin-3 (IL-3) Mouse Monoclonal Antibody [Clone IL3/4005] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Interleukin-3 (IL-3) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IL3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interleukin-3 (IL-3), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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