IHC (Immunohiostchemistry)
(Immunohistochemistry of IRAK in rat liver tissue with IRAK antibody at 5 μg/mL.)
Mouse anti-Human, Mouse IRAK Monoclonal Antibody | anti-IRAK1 antibody
IRAK Antibody [8F1A7]
Gene Names
IRAK1; IRAK; pelle
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
IRAK Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Synonyms
IRAK, Antibody; IRAK Antibody [8F1A7]; IRAK Antibody [8F1A7] : IRAK; pelle; interleukin-1 receptor-associated kinase 1; anti-IRAK1 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
8F1A7
Purity/Purification
IRAK Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
712
Applicable Applications for anti-IRAK1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Recombinant protein corresponding to amino acids 618 - 712 of human IRAK.
Buffer
IRAK Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
IRAK monoclonal antibody can be stored at -20 degree C, stable for one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of IRAK in rat liver tissue with IRAK antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of IRAK in rat liver tissue with IRAK antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of IRAK in mouse liver lysate with IRAK antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of IRAK in mouse liver lysate with IRAK antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-IRAK1 antibody
IRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-κB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
68,022 Da
NCBI Official Full Name
Interleukin-1 receptor-associated kinase 1
NCBI Official Synonym Full Names
interleukin-1 receptor-associated kinase 1
NCBI Official Symbol
IRAK1
NCBI Official Synonym Symbols
IRAK; pelle
NCBI Protein Information
interleukin-1 receptor-associated kinase 1; IRAK-1; Pelle homolog
UniProt Protein Name
Interleukin-1 receptor-associated kinase 1
UniProt Gene Name
IRAK1
UniProt Synonym Gene Names
IRAK; IRAK-1
UniProt Entry Name
IRAK1_HUMAN
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Product Notes
The IRAK1 irak1 (Catalog #AAA39206) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IRAK Antibody [8F1A7] reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IRAK can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IRAK1 irak1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRAK, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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