Rabbit KAT8 Monoclonal Antibody | anti-KAT8 antibody

KAT8 Antibody

Cat. Num. AAA30487

• Gene Names: KAT8; MOF; hMOF; MYST1; ZC2HC8
• Reactivity: Human, Rat, Mouse
• Applications: Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Flow Cytometry, Functional Assay
• Purity: ProA affinity purified
• Synonyms: KAT8, Antibody; KAT8 Antibody; Histone acetyltransferase KAT8 antibody; Histone acetyltransferase MYST1 antibody; hMOF antibody; K (lysine) acetyltransferase 8 antibody; KAT 8 antibody; Lysine acetyltransferase 8 antibody; MOF antibody; MOZ antibody; MOZ; YBF2/SAS3; SAS2 and TIP60 protein 1 antibody; MYST 1 antibody; MYST histone acetyltransferase 1 antibody; myst protein 1 antibody; MYST-1 antibody; MYST1 antibody; MYST1_HUMAN antibody; Ortholog of Drosophila males absent on the first (MOF) antibody; Probable histone acetyltransferase MYST1 antibody; SAS2 antibody; SAS3 antibody; TIP60 protein 1 antibody; YBF2 antibody; YBF2/SAS3 antibody; ZC2HC8 antibody; anti-KAT8 antibody

• Host: Rabbit
• Reactivity: Human, Rat, Mouse
• Clonality: Monoclonal
• Clone Number: JG36-05
• Purity/Purification: ProA affinity purified
• Form/Format: 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Applicable Applications for anti-KAT8 antibody: Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF),Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
• Application Notes: IHC: 1:50-1:200; ICC: 1:50-1:200; FC/FACS: 1:50-1:100
• Antibody Type: Recombinant Antibody
• Immunogen: Recombinant protein within N-terminal human KAT8.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C.

FCM (Flow Cytometry)

(Flow cytometric analysis of K562 cells with KAT8 antibody at 1/100 dilution (yellow) compared with an unlabelled control (cells without incubation with primary antibody; purple).Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.)

ICC (Immunocytochemistry)

(ICC staining KAT8 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining KAT8 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

ICC (Immunocytochemistry)

(ICC staining KAT8 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded rat cervix tissue using anti-KAT8 antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human cervix cancer tissue using anti-KAT8 antibody. Counter stained with hematoxylin.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human cervix tissue using anti-KAT8 antibody. Counter stained with hematoxylin.)

Related Product Information for anti-KAT8 antibody

Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases.

Product Categories/Family for anti-KAT8 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 68565938
• NCBI GeneID: 84148
• UniProt Accession #: Q9H7Z6; Q659G0; Q7LC17; Q8IY59; Q8WYB4; Q8WZ14; Q9HAC5; Q9NR35; A8K4Z1; G5E9P2
• Molecular Weight: 458
• NCBI Official Full Name: Histone acetyltransferase KAT8
• NCBI Official Synonym Full Names: K(lysine) acetyltransferase 8
• NCBI Official Symbol: KAT8
• NCBI Official Synonym Symbols: MOF; hMOF; MYST1; ZC2HC8
• NCBI Protein Information: histone acetyltransferase KAT8; MYST-1; lysine acetyltransferase 8; histone acetyltransferase MYST1; MYST histone acetyltransferase 1; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; probable histone acetyltransferase MYST1; ortholog of Drosophila males absent
• UniProt Protein Name: Histone acetyltransferase KAT8
• UniProt Gene Name: KAT8
• UniProt Synonym Gene Names: MOF; MYST1; MYST-1; hMOF
• UniProt Entry Name: KAT8_HUMAN