IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HMOF/MYST1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit HMOF/MYST1 Polyclonal Antibody | anti-KAT8 antibody
HMOF/MYST1 Antibody (C-term)
Gene Names
KAT8; MOF; hMOF; MYST1; ZC2HC8
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
HMOF/MYST1, Antibody; HMOF/MYST1 Antibody (C-term); Histone acetyltransferase KAT8; Lysine acetyltransferase 8; MOZ; YBF2/SAS3; SAS2 and TIP60 protein 1; MYST-1; hMOF; KAT8; MOF; MYST1; anti-KAT8 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This HMOF/MYST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human HMOF/MYST1.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
409-439
Sequence Length
467
Applicable Applications for anti-KAT8 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HMOF/MYST1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HMOF/MYST1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of anti-HMOF/MYST1(C-term) Pab in K562 cell line lysates (35ug/lane). HMOF/MYST1(arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of anti-HMOF/MYST1(C-term) Pab in K562 cell line lysates (35ug/lane). HMOF/MYST1(arrow) was detected using the purified Pab.)
Related Product Information for anti-KAT8 antibody
The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3; MIM 601408), yeast YBF2 and SAS2, and TIP60 (HTATIP; MIM 601409). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin (Neal et al., 2000 [PubMed 10786633]).[supplied by OMIM].
References
Rea,S.,Oncogene 26 (37), 5385-5394 (2007)
Pfister,S.,Int. J. Cancer 122 (6), 1207-1213 (2008)
Gupta,A.,Mol. Cell. Biol. 28 (1), 397-409 (2008)
Pfister,S.,Int. J. Cancer 122 (6), 1207-1213 (2008)
Gupta,A.,Mol. Cell. Biol. 28 (1), 397-409 (2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52403
NCBI Official Full Name
histone acetyltransferase KAT8 isoform 1
NCBI Official Synonym Full Names
K(lysine) acetyltransferase 8
NCBI Official Symbol
KAT8
NCBI Official Synonym Symbols
MOF; hMOF; MYST1; ZC2HC8
NCBI Protein Information
histone acetyltransferase KAT8
UniProt Protein Name
Histone acetyltransferase KAT8
UniProt Gene Name
KAT8
UniProt Synonym Gene Names
MOF; MYST1; MYST-1; hMOF
UniProt Entry Name
KAT8_HUMAN
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Product Notes
The KAT8 kat8 (Catalog #AAA283911) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 409-439. The HMOF/MYST1 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's HMOF/MYST1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the KAT8 kat8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HMOF/MYST1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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