Application Data
(Keratocan localisation in the Embryonic cornea on days 13,15, and 18.)
Mouse Keratocan Monoclonal Antibody | anti-KERA antibody
Monocloncal Antibody to Keratocan (Clone Ker-1)
Gene Names
KERA; KTN; CNA2; SLRR2B
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity purified on thiophilic column
Synonyms
Keratocan, Antibody; Monocloncal Antibody to Keratocan (Clone Ker-1); Keratocan Antibody; KERA; CNA2; Keratan sulfate proteoglycans (KSPGs); O60938; KTN; SLRR2B; anti-KERA antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgM
Clone Number
Ker-1
Specificity
This Keratocan antibody recognises a protein core epitope in human, bovine, porcine, mouse & chicken tissues.
Purity/Purification
Affinity purified on thiophilic column
Form/Format
Liquid; PBS, no preservatives
Concentration
0.1 mg/mL (varies by lot)
Sequence Length
352
Applicable Applications for anti-KERA antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Note
This epitope is best recognized after keratanase and keratanase II treatment/diges-tion of section (IHC) or tissue extracts (for Western analyses). In some IHC tissue analyses, chondroitinase treatment may also be used as this second enzyme treatment facilitates antibody penetration into the tissue.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Application Data
(Keratocan localisation in the Embryonic cornea on days 13,15, and 18.)
Application Data
(Keratocan localisation in the Embryonic cornea on days 13,15, and 18.)
WB (Western Blot)
(Western Blot using anti-Keratocan at a concentration of 0.4 ug/mL)
WB (Western Blot)
(Western Blot using anti-Keratocan at a concentration of 0.4 ug/mL)
Application Data
(Species Reactivty with Ker-1. Samples are treated with Kera-tanase and Keratanase II prior to electrophoresis.)
Application Data
(Species Reactivty with Ker-1. Samples are treated with Kera-tanase and Keratanase II prior to electrophoresis.)
Related Product Information for anti-KERA antibody
Keratocan belongs to the Small Leucine Rich Proteoglycan (SLRP) family. It was originally found to be a cornea specific keratan sulphate proteoglycan that, along with Lumican, plays a role in the development and maintenance of corneal transparency. Mutations of keratocan cause cornea plana in humans, which is often associated with glaucoma, whereas the absence of Lumican leads to formation of cloudy corneas. This suggests that Keratocan and Lumican have different roles in regulating the formation of stromal extracellular matrix.
Product Categories/Family for anti-KERA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
keratocan
NCBI Official Synonym Full Names
keratocan
NCBI Official Symbol
KERA
NCBI Official Synonym Symbols
KTN; CNA2; SLRR2B
NCBI Protein Information
keratocan; keratan sulfate proteoglycan keratocan
UniProt Protein Name
Keratocan
UniProt Gene Name
KERA
UniProt Synonym Gene Names
SLRR2B; KTN
UniProt Entry Name
KERA_HUMAN
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Product Notes
The KERA kera (Catalog #AAA63030) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Keratocan can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KERA kera for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Keratocan, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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