FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of 293T cells with KPNA2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).)
Rabbit KPNA2 Monoclonal Antibody | anti-KPNA2 antibody
KPNA2 Antibody
Gene Names
KPNA2; QIP2; RCH1; IPOA1; SRP1alpha
Reactivity
Human, Mouse, Rat
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
ProA affinity purified
Synonyms
KPNA2, Antibody; KPNA2 Antibody; IMA1_HUMAN antibody; Importin alpha 1 antibody; Importin alpha 2 antibody; Importin alpha 2 subunit antibody; Importin alpha P1 antibody; Importin subunit alpha-1 antibody; IPO A1 antibody; IPOA 1 antibody; IPOA1 antibody; Karyopherin alpha 2 antibody; Karyopherin alpha 2 RAG cohort 1 antibody; Karyopherin alpha 2 subunit antibody; Karyopherin subunit alpha-2 antibody; KPNA2 antibody; KPNA2 protein antibody; Pendulin antibody; QIP 2 antibody; QIP2 antibody; RAG cohort 1 antibody; RAG cohort protein 1 antibody; RCH 1 antibody; RCH1 antibody; SRP 1 antibody; SRP1 alpha antibody; SRP1 antibody; SRP1-alpha antibody; SRP1alpha antibody; anti-KPNA2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-KPNA2 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of 293T cells with KPNA2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of 293T cells with KPNA2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).)
WB (Western Blot)
(Western blot analysis of KPNA2 on different cell lysates using anti-KPNA2 antibody at 1/1, 000 dilution. Postive control: Lane 1: Hela Lane 2: 293T Lane 3: HepG2 Lane 4: NIH-3T3 Lane 5: PC-12)
WB (Western Blot)
(Western blot analysis of KPNA2 on different cell lysates using anti-KPNA2 antibody at 1/1, 000 dilution. Postive control: Lane 1: Hela Lane 2: 293T Lane 3: HepG2 Lane 4: NIH-3T3 Lane 5: PC-12)
Related Product Information for anti-KPNA2 antibody
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Product Categories/Family for anti-KPNA2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
529
NCBI Official Full Name
Importin subunit alpha-1
NCBI Official Synonym Full Names
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
NCBI Official Symbol
KPNA2
NCBI Official Synonym Symbols
QIP2; RCH1; IPOA1; SRP1alpha
NCBI Protein Information
importin subunit alpha-1; pendulin; SRP1-alpha; RAG cohort 1; importin alpha 1; importin alpha 2; importin-alpha-P1; RAG cohort protein 1; importin subunit alpha-2; karyopherin subunit alpha-2
UniProt Protein Name
Importin subunit alpha-1
UniProt Gene Name
KPNA2
UniProt Synonym Gene Names
RCH1; SRP1
UniProt Entry Name
IMA1_HUMAN
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Product Notes
The KPNA2 kpna2 (Catalog #AAA312544) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KPNA2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KPNA2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the KPNA2 kpna2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KPNA2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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