Host
Mouse
Clonality
Monoclonal
Isotype
Mouse IgG1
Purity/Purification
Protein G
Form/Format
0.2 um filtered in PBS+0.1%BSA+0.02%NaN3
Concentration
1.39mg/mL (varies by lot)
Sequence Length
475
Applicable Applications for anti-LTF antibody
WB (Western Blot), IA (Immunoassay)
Cross reactivity
Human lactoferrin: Weak
Korean goat lactoferrin: Weak
Bovine transferrin: Slight
Human transferrin: No
Chicken ovotransferrin: No
Korean goat lactoferrin: Weak
Bovine transferrin: Slight
Human transferrin: No
Chicken ovotransferrin: No
Preparation and Storage
Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for one year.
Related Product Information for anti-LTF antibody
Product Description: Monoclonal antibody a-bC-lobe, anti bovine Lactoferrin (Lf) is highly specific for bovine Lactoferrin. This protein is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. It shows multifunctional properties of which the bacteriostatic and bactericidal effects are the best known. The molecule is constructed with a N-terminal half molecule (N-lobe) and a C-terminal half molecule (C-lobe), each of which is composed of two domains. The biologically important functions have been found mainly in the N-lobe. The lactoferrin determinants responsible for binding to Ca2+-dependent receptor on hepatocytes are present within the C-lobe. The monoclonal antibody a-bC-lobe shows strong reactivities with both native and denatured forms of bovine lactoferrin and C-lobe. The 'WNIPMGL' sequence (467-473 of bovine lactoferrin) is the antigenic determinant or epitopic site of the anti C-lobe antibody a-bC-lobe. The antibody shows weak reactivity with human lactoferrin and korean goat lactoferrin, slight cross reactivity is seen with bovine transferrin, whereas no cross reactivity is seen with human transferrin and chicken ovotransferrin.
References
1. Shimazaki, K et al; Structural and immunochemical studies on bovine lactoferrin fragments. Adv Exp Med Biol 1998, 443: 41 2. Nam, S et al; Characterization of Korean native goat lactoferrin. Comp Biochem Physiol part B 1999, 123: 201
3. Nam, S et al; Fine structures of epitopic sites in human and bovine lactoferrin recognized by anti-bovine lactoferrin C-lobe monoclonal antibody. Food and Agricultural Immunology 2002, 14: 139
3. Nam, S et al; Fine structures of epitopic sites in human and bovine lactoferrin recognized by anti-bovine lactoferrin C-lobe monoclonal antibody. Food and Agricultural Immunology 2002, 14: 139
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
lactoferrin, partial
NCBI Official Synonym Full Names
lactotransferrin
NCBI Official Symbol
LTF
NCBI Official Synonym Symbols
LF; HLF2; GIG12; HEL110
NCBI Protein Information
lactotransferrin; talalactoferrin; neutrophil lactoferrin; growth-inhibiting protein 12; epididymis luminal protein 110
UniProt Protein Name
Lactotransferrin
UniProt Gene Name
LTF
UniProt Synonym Gene Names
GIG12; LF; Lactoferrin; Lfcin-H
UniProt Entry Name
TRFL_HUMAN
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Product Notes
The LTF ltf (Catalog #AAA77786) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Lactoferrin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IA (Immunoassay). Researchers should empirically determine the suitability of the LTF ltf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lactoferrin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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