SDS-PAGE
(SDS PAGE for Lirilumab)
anti-Human Lirilumab Monoclonal Antibody | anti-KIR2DL1 antibody
Research Grade Lirilumab
Gene Names
KIR2DL1; NKAT; NKAT1; p58.1; CD158A; KIR221; NKAT-1; KIR-K64
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Lirilumab, Antibody; Research Grade Lirilumab; BMS-986015; IPH2102; CD158 antigen-like family member A; KIR2DL1; Killer cell immunoglobulin-like receptor 2DL1; Natural killer-associated transcript 1; NKAT-1; MHC class I NK cell receptor; CD158A; p58 natural killer cell receptor clones CL-42/47.11; p58.1 MHC class-I-specific NK receptor; NKAT1; p58 NK receptor CL-42/47.11; anti-KIR2DL1 antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG4-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Human
CAS
1000676-41-4
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Lirilumab)
SDS-PAGE
(SDS PAGE for Lirilumab)
Bioactivity
(Detects Human CD158b1/KIR2DL2 in direct ELISAs.)
Bioactivity
(Detects Human CD158b1/KIR2DL2 in direct ELISAs.)
Product Categories/Family for anti-KIR2DL1 antibody
References
A phase 1 study of lirilumab (antibody against killer immunoglobulin-like receptor antibody KIR2D; IPH2102) in patients with solid tumors and hematologic malignancies, PMID: 29707140
A phase 1b study of dual PD-1 and CTLA-4 or KIR blockade in patients with relapsed/refractory lymphoid malignancies, PMID: 32601377
High affinity anti-TIM-3 and anti-KIR monoclonal antibodies cloned from healthy human individuals, PMID: 28723950
Immunogenomic correlates of response to cetuximab monotherapy in head and neck squamous cell carcinoma, PMID: 30828910
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies, PMID: 24326534
A phase 1b study of dual PD-1 and CTLA-4 or KIR blockade in patients with relapsed/refractory lymphoid malignancies, PMID: 32601377
High affinity anti-TIM-3 and anti-KIR monoclonal antibodies cloned from healthy human individuals, PMID: 28723950
Immunogenomic correlates of response to cetuximab monotherapy in head and neck squamous cell carcinoma, PMID: 30828910
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies, PMID: 24326534
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
348
NCBI Official Full Name
Killer cell immunoglobulin-like receptor 2DL1
NCBI Official Synonym Full Names
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
NCBI Official Symbol
KIR2DL1
NCBI Official Synonym Symbols
NKAT; NKAT1; p58.1; CD158A; KIR221; NKAT-1; KIR-K64
NCBI Protein Information
killer cell immunoglobulin-like receptor 2DL1; killer Ig receptor; p58 NK receptor CL-42/47.11; MHC class I NK cell receptor; killer inhibitory receptor 2-2-1; CD158 antigen-like family member A; natural killer-associated transcript 1; p58 NK cell inhibit
UniProt Protein Name
Killer cell immunoglobulin-like receptor 2DL1
UniProt Gene Name
KIR2DL1
UniProt Synonym Gene Names
CD158A; NKAT1; NKAT-1; p58 NK receptor CL-42/47.11
UniProt Entry Name
KI2L1_HUMAN
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Product Notes
The KIR2DL1 kir2dl1 (Catalog #AAA120084) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Lirilumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Lirilumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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