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FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of K562 cells using LMO2 Mouse Monoclonal Antibody (LMO2/1971) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red))
Mouse anti-Human LMO2 Monoclonal Antibody | anti-LMO2 antibody
LMO2 (B-Cell Marker)
Gene Names
LMO2; TTG2; LMO-2; RBTN2; RHOM2; RBTNL1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, Flow Cytometry, Functional Assay
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
LMO2, Antibody; LMO2 (B-Cell Marker); Cysteine-rich protein TTG-2; LIM domain only protein 2; LMO-2; RBTN L1; RBTN2; Rhombotin like 1; Rhombotin-2 (RHOM2); T-cell translocation protein 2; TTG2; anti-LMO2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b, kappa
Clone Number
LMO2/1971
Specificity
The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin's and Burkitt s lymphomas.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
158
Applicable Applications for anti-LMO2 antibody
IHC (Immunohistochemistry), WB (Western Blot), FCM/FACS (Flow Cytometry)
Positive Control
K562 or Hodgkin s lymphoma, Ramos or Raji cells. Human placenta, pancreas and Brain
Immunogen
Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)
Cellular Localization
Nuclear
Hu-chromosome Location
11p13
Research Areas
Cardiovascular, Nuclear Marker, Stem Cell Differentiation, Transcription Factors
Preparation and Storage
Antibody with azide: store at 2 to 8 degrees C.
Antibody without azide: store at -20 to -80 degrees C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degrees C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of K562 cells using LMO2 Mouse Monoclonal Antibody (LMO2/1971) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red))
FCM/FACS (Flow Cytometry)
(Flow Cytometric Analysis of K562 cells using LMO2 Mouse Monoclonal Antibody (LMO2/1971) followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red))
Application Data
(Purified LMO2 Mouse Monoclonal Antibody (LMO2/1971). Confirmation of Purity and Integrity of Antibody.)
Application Data
(Purified LMO2 Mouse Monoclonal Antibody (LMO2/1971). Confirmation of Purity and Integrity of Antibody.)
WB (Western Blot)
(Western Blot Analysis of Human Brain tissue lysate using LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
WB (Western Blot)
(Western Blot Analysis of Human Brain tissue lysate using LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
WB (Western Blot)
(Western Blot Analysis of Ramos cell lysate using LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
WB (Western Blot)
(Western Blot Analysis of Ramos cell lysate using LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Pancreas stained with LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human Pancreas stained with LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Follicular Lymphoma stained with LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Follicular Lymphoma stained with LMO2 Mouse Monoclonal Antibody (LMO2/1971).)
References
Younes, SF et al. Am J Clin Pathol. 2011 May;135(5):697-708.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
24kDa
NCBI Official Full Name
Rhombotin-2
NCBI Official Synonym Full Names
LIM domain only 2
NCBI Official Symbol
LMO2
NCBI Official Synonym Symbols
TTG2; LMO-2; RBTN2; RHOM2; RBTNL1
NCBI Protein Information
rhombotin-2
UniProt Protein Name
Rhombotin-2
UniProt Gene Name
LMO2
UniProt Synonym Gene Names
RBTN2; RBTNL1; RHOM2; TTG2; LMO-2
UniProt Entry Name
RBTN2_HUMAN
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Product Notes
The LMO2 lmo2 (Catalog #AAA215068) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LMO2 (B-Cell Marker) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LMO2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the LMO2 lmo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LMO2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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