Application Data
(Detection of LRRK2 in neuroblastoma cell line SK-N-BE at 10ug/ml: DAPI (blue) nuclear stain, Texas Red F actin stain, ATTO 488 (green) LRRK2 stain.)
Mouse LRRK2/Dardarin Monoclonal Antibody | anti-LRRK2 antibody
LRRK2 / Dardarin Monoclonal Antibody
Gene Names
LRRK2; PARK8; RIPK7; ROCO2; AURA17; DARDARIN
Applications
Immunofluorescence, Immunoblot, Western Blot
Synonyms
LRRK2/Dardarin, Antibody; LRRK2 / Dardarin Monoclonal Antibody; anti-LRRK2 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody recognizes human, mouse and rat LRRK2.
Form/Format
100ug (1mg/ml) Protein G-purified antibody in PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
Sequence Length
2527
Applicable Applications for anti-LRRK2 antibody
IF (Immunofluorescence), IB (Immunoblot)
Immunogen
Fusion protein corresponding to aa 1-500 (N-terminus) of human LRRK2. This sequence is 83% identical in mouse and rat and has no significant identity to LRRK1.
Preparation and Storage
This product is stable for at least one (1) year at-20 degree C.
Application Data
(Detection of LRRK2 in neuroblastoma cell line SK-N-BE at 10ug/ml: DAPI (blue) nuclear stain, Texas Red F actin stain, ATTO 488 (green) LRRK2 stain.)
Application Data
(Detection of LRRK2 in neuroblastoma cell line SK-N-BE at 10ug/ml: DAPI (blue) nuclear stain, Texas Red F actin stain, ATTO 488 (green) LRRK2 stain.)
Application Data
(Detection of LRRK2 in rat brain lysate at 5ug/ml.)
Application Data
(Detection of LRRK2 in rat brain lysate at 5ug/ml.)
Related Product Information for anti-LRRK2 antibody
LRRK2 is a large protein (>200kDa) with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Raslike small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. The LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. LRRK2 is also known as Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin, and PARK8.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
286,103 Da
NCBI Official Full Name
leucine-rich repeat serine/threonine-protein kinase 2
NCBI Official Synonym Full Names
leucine rich repeat kinase 2
NCBI Official Symbol
LRRK2
NCBI Official Synonym Symbols
PARK8; RIPK7; ROCO2; AURA17; DARDARIN
NCBI Protein Information
leucine-rich repeat serine/threonine-protein kinase 2
UniProt Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
UniProt Gene Name
LRRK2
UniProt Synonym Gene Names
PARK8
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Product Notes
The LRRK2 lrrk2 (Catalog #AAA47870) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LRRK2/Dardarin can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IB (Immunoblot). Researchers should empirically determine the suitability of the LRRK2 lrrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRRK2/Dardarin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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