SDS-PAGE
(SDS-PAGE Analysis Purified LHCGR Mouse Monoclonal Antibody (LHCGR/1416). Confirmation of Integrity and Purity of Antibody.)
Mouse Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody | anti-LHCGR antibody
Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR)
Gene Names
LHCGR; HHG; LHR; LCGR; LGR2; ULG5; LHRHR; LSH-R; LH/CGR; LH/CG-R
Reactivity
Human. Others not known.
Applications
Western Blot, Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR), Antibody; Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR); Gonadotropin receptor; GTHR-II; HHG; LCGR; LGR2; LH-R; LH/CG-R; LH/CGR; LHCGR; LHR; LHRHR; LSH-R; Luteinizing hormone receptor; Luteinizing hormone/choriogonadotropin receptor; Lutropin choriogonadotropic receptor; Lutropin-choriogonadotropic hormone receptor; ULG5; anti-LHCGR antibody
Host
Mouse
Reactivity
Human. Others not known.
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
LHCGR/1416
Specificity
Recognizes a protein of 78-85kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Form/Format
1.0mg/mL of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS
Sequence Length
699
Applicable Applications for anti-LHCGR antibody
WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
Cellular Localization
Cytoplasmic and Cell Surface
Hu-chromosome Location
2p21
Positive Control
HepG2 or Jurkat cells. Ovary or Testis.
Preparation and Storage
Antibody without azide - store at -20 to -80 degree C.
Non-hazardous. No MSDS required.
Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified LHCGR Mouse Monoclonal Antibody (LHCGR/1416). Confirmation of Integrity and Purity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified LHCGR Mouse Monoclonal Antibody (LHCGR/1416). Confirmation of Integrity and Purity of Antibody.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Cervix stained with Cytokeratin 14 Monoclonal Antibody (KRT14/532).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Cervix stained with Cytokeratin 14 Monoclonal Antibody (KRT14/532).)
References
Pidoux, G., et al. 2007. Biochemical characterization and modulation of LH/CG-receptor during human trophoblast differentiation. J. Cell. Physiol. 212: 26-35.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78-85kDa
NCBI Official Full Name
lutropin-choriogonadotropic hormone receptor
NCBI Official Synonym Full Names
luteinizing hormone/choriogonadotropin receptor
NCBI Official Symbol
LHCGR
NCBI Official Synonym Symbols
HHG; LHR; LCGR; LGR2; ULG5; LHRHR; LSH-R; LH/CGR; LH/CG-R
NCBI Protein Information
lutropin-choriogonadotropic hormone receptor
UniProt Protein Name
Lutropin-choriogonadotropic hormone receptor
UniProt Gene Name
LHCGR
UniProt Synonym Gene Names
LCGR; LGR2; LHRHR; LH/CG-R; LHR; LSH-R
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Product Notes
The LHCGR lhcgr (Catalog #AAA214432) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the LHCGR lhcgr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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