IP (Immunoprecipitation)
(Immunoprecipitation of MAPK8 transfected lysate using anti-MAPK8 monoclonal antibody and Protein A magnetic bead, immunoblotted with MAPK8 rabbit polyclonal antibody.)
Mouse anti-Human MAPK8 / JNK1 / JNK Monoclonal Antibody | anti-MAPK8 antibody
Mouse Monoclonal [clone 3H2] (IgG2a,k) to Human MAPK8 / JNK1 / JNK
Gene Names
MAPK8; JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
Reactivity
Human
Applications
ELISA, Immunoprecipitation, Western Blot, Immunohistochemistry
Purity
Protein A Purified
Synonyms
MAPK8 / JNK1 / JNK, Antibody; Mouse Monoclonal [clone 3H2] (IgG2a,k) to Human MAPK8 / JNK1 / JNK; Anti-MAPK8 / JNK1 / JNK Antibody (clone 3H2) IHC-plus; MAPK8; JNK; JNK1; JNK1A2; JNK-46; MAP kinase 8; PRKM8; SAPK1; SAPK1c; MAPK 8; C-Jun N-terminal kinase 1; JNK21B1/2; JUN N-terminal kinase; Human MAPK8; anti-MAPK8 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3H2
Specificity
Human MAPK8 / JNK1
Purity/Purification
Protein A Purified
Form/Format
PBS, pH 7.2. Sourced in Ascites.
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
427
Applicable Applications for anti-MAPK8 antibody
ELISA, IP (Immunoprecipitation), WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Recombinant protein encoding amino acids 318 to 427 of NP_620637
Immunogen Type
Recombinant protein
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
IP (Immunoprecipitation)
(Immunoprecipitation of MAPK8 transfected lysate using anti-MAPK8 monoclonal antibody and Protein A magnetic bead, immunoblotted with MAPK8 rabbit polyclonal antibody.)
IP (Immunoprecipitation)
(Immunoprecipitation of MAPK8 transfected lysate using anti-MAPK8 monoclonal antibody and Protein A magnetic bead, immunoblotted with MAPK8 rabbit polyclonal antibody.)
WB (Western Blot)
(Western blot of MAPK8 expression in transfected 293T cell line by MAPK8 monoclonal antibody, clone 3H2.)
WB (Western Blot)
(Western blot of MAPK8 expression in transfected 293T cell line by MAPK8 monoclonal antibody, clone 3H2.)
IHC (Immunohistochemistry)
(Anti-MAPK8 / JNK1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
IHC (Immunohistochemistry)
(Anti-MAPK8 / JNK1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.)
Related Product Information for anti-MAPK8 antibody
JNK1, a MAPK type protein kinase, regulates cell apoptosis, differentiation and growth in response to growth factors, inflammatory cytokines and cellular stress. JNK1 is phosphorylated by MKK4/MAP2K4 and MKK7/MAP2K7. Activated JNK1 translocates to the nucleus where it phosphorylates transcription factors, including c-Jun, ATF2, ELK1, Jun-D and NFAT4. At least four alternatively spliced transcript variants encoding distinct isoforms, 384 and 427 amino acids, have been identified.
Product Categories/Family for anti-MAPK8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,333 Da
NCBI Official Full Name
mitogen-activated protein kinase 8 isoform alpha2
NCBI Official Synonym Full Names
mitogen-activated protein kinase 8
NCBI Official Symbol
MAPK8
NCBI Official Synonym Symbols
JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
NCBI Protein Information
mitogen-activated protein kinase 8; MAP kinase 8; JUN N-terminal kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase 1c; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 isoform JNK1 alpha1
UniProt Protein Name
Mitogen-activated protein kinase 8
UniProt Gene Name
MAPK8
UniProt Synonym Gene Names
JNK1; PRKM8; SAPK1; SAPK1C; MAP kinase 8; MAPK 8; SAPK1c
UniProt Entry Name
MK08_HUMAN
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Product Notes
The MAPK8 mapk8 (Catalog #AAA51887) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone 3H2] (IgG2a,k) to Human MAPK8 / JNK1 / JNK reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAPK8 / JNK1 / JNK can be used in a range of immunoassay formats including, but not limited to, ELISA, IP (Immunoprecipitation), WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the MAPK8 mapk8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAPK8 / JNK1 / JNK, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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