Mouse MEK-2 Monoclonal Antibody | anti-MEK-2 antibody

MEK-2 Monoclonal Antibody

Cat. Num. AAA320154

• Gene Names: MAP2K2; CFC4; MEK2; MKK2; MAPKK2; PRKMK2
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Western Blot
• Purity: Affinity purification
• Synonyms: MEK-2, Antibody; MEK-2 Monoclonal Antibody; Dual specificity mitogen-activated protein kinase kinase 2; MAP2K2; MEK2; MKK2; PRKMK2; MAP kinase kinase 2; MAPKK 2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2; anti-MEK-2 antibody

• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Specificity: MEK-2 Monoclonal Antibody detects endogenous levels of MEK-2 protein.
• Purity/Purification: Affinity purification
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-MEK-2 antibody: ELISA, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot)
• Immunogen: Purified recombinant fragment of human MEK-2 expressed in E coli.
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of Hela cells using MEK-2 Monoclonal Antibody (green) and negative control (purple).)

IF (Immunofluorescence)

(Immunofluorescence analysis of Hela cells using MEK-2 Monoclonal Antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.)

WB (Western Blot)

(Western Blot analysis using MEK-2 Monoclonal Antibody against PC-12 (1). Jurkat (2). HeLa (3) and NIH/3T3 (4) cell lysate.)

Related Product Information for anti-MEK-2 antibody

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]

Product Categories/Family for anti-MEK-2 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 547915
• NCBI GeneID: 5605
• UniProt Accession #: P36507
• Molecular Weight: 400
• NCBI Official Full Name: Dual specificity mitogen-activated protein kinase kinase 2
• NCBI Official Synonym Full Names: mitogen-activated protein kinase kinase 2
• NCBI Official Symbol: MAP2K2
• NCBI Official Synonym Symbols: CFC4; MEK2; MKK2; MAPKK2; PRKMK2
• NCBI Protein Information: dual specificity mitogen-activated protein kinase kinase 2; MAPK/ERK kinase 2; MAP kinase kinase 2; ERK activator kinase 2; mitogen-activated protein kinase kinase 2, p45
• UniProt Protein Name: Dual specificity mitogen-activated protein kinase kinase 2
• UniProt Gene Name: MAP2K2
• UniProt Synonym Gene Names: MEK2; MKK2; PRKMK2; MAP kinase kinase 2; MAPKK 2; MEK 2
• UniProt Entry Name: MP2K2_HUMAN