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IF (Immunofluorescence)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
Mouse MICU1 Monoclonal Antibody | anti-MICU1 antibody
MICU1 Monoclonal Antibody (Mix)
Gene Names
MICU1; CALC; EFHA3; MPXPS; CBARA1
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Synonyms
MICU1, Antibody; MICU1 Monoclonal Antibody (Mix); Calcium uptake protein 1; mitochondrial; Atopy-related autoantigen CALC; ara CALC; Calcium-binding atopy-related autoantigen 1; allergen Hom s 4; anti-MICU1 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
Mix
Applicable Applications for anti-MICU1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IF (Immunofluorescence)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
IF (Immunofluorescence)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
IHC (Immunohistochemisry)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
IHC (Immunohistochemisry)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
IHC (Immunohiostchemistry)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
IHC (Immunohiostchemistry)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
WB (Western Blot)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
WB (Western Blot)
(Dilution: WB: 1:1000-2000 IHC: 1:100-200 IF 1:200)
Related Product Information for anti-MICU1 antibody
Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (PubMed:23101630, PubMed:23747253, PubMed:24313810, PubMed:24332854, PubMed:24503055, PubMed:24560927, PubMed:26341627, PubMed:26903221, PubMed:27099988). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium. MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (PubMed:26903221). Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (PubMed:22904319). Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (PubMed:16002733).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,931 Da
NCBI Official Full Name
calcium uptake protein 1, mitochondrial isoform 1
NCBI Official Synonym Full Names
mitochondrial calcium uptake 1
NCBI Official Symbol
MICU1
NCBI Official Synonym Symbols
CALC; EFHA3; MPXPS; CBARA1
NCBI Protein Information
calcium uptake protein 1, mitochondrial; ara CALC; atopy-related autoantigen CALC; calcium-binding atopy-related autoantigen 1
UniProt Protein Name
Calcium uptake protein 1, mitochondrial
UniProt Gene Name
MICU1
UniProt Synonym Gene Names
CALC; CBARA1; ara CALC
UniProt Entry Name
MICU1_HUMAN
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Product Notes
The MICU1 micu1 (Catalog #AAA293665) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MICU1 Monoclonal Antibody (Mix) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MICU1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MICU1 micu1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MICU1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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