anti-Human Mirikizumab Monoclonal Antibody | anti-IL23A antibody
Research Grade Mirikizumab
Gene Names
IL23A; P19; SGRF; IL-23; IL-23A; IL23P19
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Mirikizumab, Antibody; Research Grade Mirikizumab; LY-3074828; SGRF; IL-23-A; IL-23 subunit alpha; Interleukin-23 subunit p19; IL23A; Interleukin-23 subunit alpha; IL-23p19; anti-IL23A antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG4-kappa
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Humanized
CAS
1884201-71-1
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Product Categories/Family for anti-IL23A antibody
References
A SPECIAL MEETING REVIEW EDITION: Highlights in Inflammatory Bowel Disease From the 14th Congress of ECCO: A Review of Selected Presentations From the 14th Congress of the European Crohn's and Colitis Organisation (ECCO) -March 6-9, 2019 -Copenhagen, Denmark Special Reporting on -VARSITY: A Double-Blind, Double-Dummy, Randomized Controlled Trial of Vedolizumab Versus Adalimumab in Patients With Active Ulcerative Colitis-Analyses of Data From the VISIBLE 1 and 2 Trials: Vedolizumab in Patients With Ulcerative Colitis or Crohn's Disease-Improved Endoscopic Outcomes and Mucosal Healing of Upadacitinib as an Induction Therapy in Adults With Moderately to Severely Active Ulcerative Colitis: Data From the U-ACHIEVE Study Long-Term Safety of Vedolizumab in Ulcerative Colitis and Crohn's Disease: Final Results From the GEMINI LTS Study-Pediatric Crohn's Disease Adalimumab Level-Based Optimization Treatment (PAILOT) Randomized Controlled Trial-Maintenance Treatment With Mirikizumab, a P19-Directed IL-23 Antibody: 52-Week Results in Patients With Moderately to Severely Active Ulcerative Colitis-Real-World Effectiveness and Safety of Vedolizumab and Anti-TNF Therapy in Biologic-Naive Patients With Ulcerative Colitis or Crohn's Disease: Results From the EVOLVE Study-A Randomized, Multicenter, Double-Blind, Placebo-Controlled Study of a Targeted-Release Oral Cyclosporine Formulation in the Treatment of Mild to Moderate Ulcerative Colitis: Efficacy Results-Real-World Analyses of Patients With IBD Treated With Vedolizumab PLUS Meeting Abstract Summaries With Expert Commentary by: Edward V. Loftus Jr, MD Professor of MedicineDivision of Gastroenterology and HepatologyMayo ClinicRochester, Minnesota, PMID: 31632213
Anti-interleukin-12 and anti-interleukin-23 agents in Crohn's disease, PMID: 30571147
Anti-interleukin-23 agents for the treatment of ulcerative colitis, PMID: 31760827
Central Reading of Ulcerative Colitis Clinical Trial Videos Using Neural Networks, PMID: 33098883
Clinical Trials of IL-12/IL-23 Inhibitors in Inflammatory Bowel Disease, PMID: 33105016
Anti-interleukin-12 and anti-interleukin-23 agents in Crohn's disease, PMID: 30571147
Anti-interleukin-23 agents for the treatment of ulcerative colitis, PMID: 31760827
Central Reading of Ulcerative Colitis Clinical Trial Videos Using Neural Networks, PMID: 33098883
Clinical Trials of IL-12/IL-23 Inhibitors in Inflammatory Bowel Disease, PMID: 33105016
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,730 Da
NCBI Official Full Name
interleukin-23 subunit alpha
NCBI Official Synonym Full Names
interleukin 23, alpha subunit p19
NCBI Official Symbol
IL23A
NCBI Official Synonym Symbols
P19; SGRF; IL-23; IL-23A; IL23P19
NCBI Protein Information
interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; IL-23p19; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin-23 subunit p19; interleukin-six, G-CSF related factor
UniProt Protein Name
Interleukin-23 subunit alpha
UniProt Gene Name
IL23A
UniProt Synonym Gene Names
SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19
UniProt Entry Name
IL23A_HUMAN
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Product Notes
The IL23A il23a (Catalog #AAA120132) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Mirikizumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Mirikizumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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