ICC (Immunocytochemistry)
(ICC staining MKLP1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Rabbit MKLP1 Monoclonal Antibody | anti-MKLP1 antibody
MKLP1 Antibody
Gene Names
KIF23; CHO1; KNSL5; MKLP1; MKLP-1
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Western Blot
Purity
ProA affinity purified
Synonyms
MKLP1, Antibody; MKLP1 Antibody; CHO 1 antibody; CHO1 antibody; KIF 23 antibody; KIF23 antibody; KIF23_HUMAN antibody; Kinesin family member 23 antibody; Kinesin like 5 antibody; Kinesin like protein 5 antibody; Kinesin like protein KIF 23 antibody; Kinesin like protein KIF23 antibody; Kinesin-like protein 5 antibody; Kinesin-like protein KIF23 antibody; KNS L5 antibody; KNSL 5 antibody; KNSL5 antibody; Mitotic kinesin like 1 antibody; Mitotic kinesin like protein 1 antibody; Mitotic kinesin-like protein 1 antibody; MKLP 1 antibody; anti-MKLP1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Clone Number
SY02-74
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-MKLP1 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot)
Antibody Type
Recombinant Antibody
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
ICC (Immunocytochemistry)
(ICC staining MKLP1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining MKLP1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining MKLP1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining MKLP1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
WB (Western Blot)
(Western blot analysis of MKLP1 on different lysates using anti-MKLP1 antibody at 1/1, 000 dilution. Positive control: Lane 1: A549 Lane 2: Hela)
WB (Western Blot)
(Western blot analysis of MKLP1 on different lysates using anti-MKLP1 antibody at 1/1, 000 dilution. Positive control: Lane 1: A549 Lane 2: Hela)
Related Product Information for anti-MKLP1 antibody
The monoclonal antibody CHO1 detects a spindle antigen required for mitotic progression. Screening a HeLa cell cDNA expression library with this antibody has been shown to yield a cDNA predicted to encode a protein significantly related within its amino terminal half to the motor ends of members of the kinesin superfamily. Since this similarity does not extend further, it has been suggested that the CHO1 antigen, now designated MKLP-1 (mitotic kinesin-like protein-1), represents a novel kinesin. Sequence analysis has also been shown to predict that MKLP-1 possesses features typical of nuclear proteins. Immunocytological studies have demonstrated that MKLP-1 moves from the nucleus early in mitosis and then to the midbody after cytokinesis. MKLP-1 has been shown to bundle antiparallel microtubules in vitro and to move them at rates comparable to spindle elongation in vivo. A hamster homolog of MKLP-1, designated CHO1 antigen, has also been isolated. Although apparently functionally equivalent with respect to microtubule bundling activity, there are significant differences between the human and hamster proteins at their C-termini, possibly due to alternative splicing or the presence of more than one MKLP-1 locus.
Product Categories/Family for anti-MKLP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
110059 MW
NCBI Official Full Name
kinesin-like protein KIF23 isoform 2
NCBI Official Synonym Full Names
kinesin family member 23
NCBI Official Symbol
KIF23
NCBI Official Synonym Symbols
CHO1; KNSL5; MKLP1; MKLP-1
NCBI Protein Information
kinesin-like protein KIF23
UniProt Protein Name
Kinesin-like protein KIF23
UniProt Gene Name
KIF23
UniProt Synonym Gene Names
KNSL5; MKLP1
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Product Notes
The MKLP1 kif23 (Catalog #AAA312197) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MKLP1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MKLP1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MKLP1 kif23 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MKLP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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