Mouse anti-Human MMP-1 Monoclonal Antibody | anti-MMP-1 antibody

MMP-1 Monoclonal Antibody

Cat. Num. AAA320160

• Gene Names: MMP1; CLG; CLGN
• Reactivity: Human
• Applications: ELISA, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity purification
• Synonyms: MMP-1, Antibody; MMP-1 Monoclonal Antibody; Interstitial collagenase; MMP1; CLG; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1; anti-MMP-1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Specificity: MMP-1 Monoclonal Antibody detects endogenous levels of MMP-1 protein.
• Purity/Purification: Affinity purification
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applicable Applications for anti-MMP-1 antibody: ELISA, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Purified recombinant fragment of human MMP-1 expressed in E coli.
• Modification: Unmodified/Total
• Preparation and Storage: Store at -20 degree C/1 year

Application Data

FCM/FACS (Flow Cytometry)

(Flow cytometric analysis of Hela cells using MMP-1 Monoclonal Antibody (green) and negative control (purple).)

IF (Immunofluorescence)

(Immunofluorescence analysis of Hela cells using MMP-1 Monoclonal Antibody. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded human cervical cancer tissues (left) and human kidney cancer tissues (right) with DAB staining using MMP-1 Monoclonal Antibody.)

WB (Western Blot)

(Western Blot analysis using MMP-1 Monoclonal Antibody against HEK293 (1) and MMP1-hIgGFc transfected HEK293 (2) cell lysate.)

Related Product Information for anti-MMP-1 antibody

matrix metallopeptidase 1(MMP1) Homo sapiens This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Product Categories/Family for anti-MMP-1 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 4505215
• NCBI GeneID: 4312
• NCBI Accession #: NP_002412.1
• NCBI GenBank Nucleotide #: NM_002421.3
• UniProt Accession #: P03956; P08156
• Molecular Weight: 54,007 Da
• NCBI Official Full Name: interstitial collagenase isoform 1 preproprotein
• NCBI Official Synonym Full Names: matrix metallopeptidase 1 (interstitial collagenase)
• NCBI Official Symbol: MMP1
• NCBI Official Synonym Symbols: CLG; CLGN
• NCBI Protein Information: interstitial collagenase; fibroblast collagenase; matrix metalloprotease 1; matrix metalloproteinase 1
• UniProt Protein Name: Interstitial collagenase
• UniProt Gene Name: MMP1
• UniProt Synonym Gene Names: CLG; MMP-1
• UniProt Entry Name: MMP1_HUMAN