Mouse MRP1/ABCC1 (Multidrug Resistance Related Protein 1) Monoclonal Antibody | anti-MRP1 antibody
MRP1/ABCC1 (Multidrug Resistance Related Protein 1)
Gene Names
ABCC1; MRP; ABCC; GS-X; MRP1; ABC29
Reactivity
Human. Others not known.
Applications
Immunofluorescence, Flow Cytometry, Functional Assay
Synonyms
MRP1/ABCC1 (Multidrug Resistance Related Protein 1), Antibody; MRP1/ABCC1 (Multidrug Resistance Related Protein 1); ABC29; ABCC1; ATP binding cassette sub family C (CFTR/MRP) member 1; ATP-binding cassette sub-family C member 1; GSX; Leukotriene C(4) transporter; LTC4 transporter; Multidrug resistance-associated protein 1 (MRP1); anti-MRP1 antibody
Host
Mouse
Reactivity
Human. Others not known.
Clonality
Monoclonal
Isotype
IgG2a / Kappa
Clone Number
MRP1/1344
Specificity
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
1531
Applicable Applications for anti-MRP1 antibody
IF (Immunofluorescence), FCM/FACS (Flow Cytometry)
Immunogen
Recombinant full-length human ABCC1 protein
Cellular Localization
Cell membrane
Positive Control
A549 cells. Colon, Endometrium, Ovary. Testis or Tonsil.
Research Areas
Cardiovascular
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide - store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
References
Faneyte IF, Kristel PM, van de Vijver MJ. Multidrug resistance associated genes MRP1, MRP2 and MRP3 in primary and anthracycline exposed breast cancer. Anticancer Res. 2004; 24(5A):2931-9.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
190kDa
NCBI Official Full Name
multidrug resistance-associated protein 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily C member 1
NCBI Official Symbol
ABCC1
NCBI Official Synonym Symbols
MRP; ABCC; GS-X; MRP1; ABC29
NCBI Protein Information
multidrug resistance-associated protein 1
UniProt Protein Name
Multidrug resistance-associated protein 1
UniProt Gene Name
ABCC1
UniProt Synonym Gene Names
MRP; MRP1; LTC4 transporter
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Product Notes
The MRP1 abcc1 (Catalog #AAA214452) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MRP1/ABCC1 (Multidrug Resistance Related Protein 1) reacts with Human. Others not known. and may cross-react with other species as described in the data sheet. AAA Biotech's MRP1/ABCC1 (Multidrug Resistance Related Protein 1) can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the MRP1 abcc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRP1/ABCC1 (Multidrug Resistance Related Protein 1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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