IHC (Immunohistochemisry)
(Immunohistochemical analysis of mTLR3 in human Liver tissue using mTLR3 antibody (Clone:ABM24ES) at 10 ug/ml.)
Rat anti-Mouse, Human mTLR3 Monoclonal Antibody | anti-mTLR3 antibody
Monoclonal Antibody to mTLR3 (ABM24E5)
Gene Names
Tlr3; AI957183
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay, Western Blot
Purity
Protein G Chromatography
Synonyms
mTLR3, Antibody; Monoclonal Antibody to mTLR3 (ABM24E5); Tlr3; anti-mTLR3 antibody
Host
Rat
Reactivity
Mouse, Human
Clonality
Monoclonal
Isotype
Rat IgG2b, Kappa
Clone Number
ABM24E5
Purity/Purification
Protein G Chromatography
Form/Format
Purified (Liquid)
Sequence Length
905
Applicable Applications for anti-mTLR3 antibody
IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), WB (Western Blot)
Antigen
mTLR3
Content
100 ug in 200ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Immunogen
A partial length recombinant mTLR3 protein (Amino acid sequence 180-385) was used as the immunogen for this antibody.
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid
repeated freeze and thaw cycles.
IHC (Immunohistochemisry)
(Immunohistochemical analysis of mTLR3 in human Liver tissue using mTLR3 antibody (Clone:ABM24ES) at 10 ug/ml.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of mTLR3 in human Liver tissue using mTLR3 antibody (Clone:ABM24ES) at 10 ug/ml.)
FCM/FACS (Flow Cytometry)
(Intracellular flow analysis of mTLR3 in m Splenocytes using 0.5 tJg/1 0"6 cells of mTLR3 antibody (Clone: ABM24E5). Green represents isotype control; red represents anti-mTLR3 antibody. Goat anti-Rat FITe conjugate was used as secondary antibody .)
FCM/FACS (Flow Cytometry)
(Intracellular flow analysis of mTLR3 in m Splenocytes using 0.5 tJg/1 0"6 cells of mTLR3 antibody (Clone: ABM24E5). Green represents isotype control; red represents anti-mTLR3 antibody. Goat anti-Rat FITe conjugate was used as secondary antibody .)
WB (Western Blot)
(Western Blot analysis of mTLR3. Anti- mTLR3 antibody (Clone: ABM24E5) was used at 2 ug/ml on mouse brain lysate.)
WB (Western Blot)
(Western Blot analysis of mTLR3. Anti- mTLR3 antibody (Clone: ABM24E5) was used at 2 ug/ml on mouse brain lysate.)
Related Product Information for anti-mTLR3 antibody
Mouse Toll-like receptor 3 (mTLR3) belongs to a family of evolutionary conserved innate immune recognition molecules and recognizes double-stranded RNA, a molecular pattern associated with viral infections. It has seven exons. mTlr3 show high homology to hTLR3 in their predicted cDNA and protein sequences. The intracellular region of mTlr3 has remarkable homology with the same region of others mTlrs. mTlr3 mRNA is ubiquitously expressed in tissues, being expressed highest in spleen, kidney and lung. Its activation by the synthetic ligand polyinosine:polycytidylic acid (poly I:C) or by mRNA rapidly causes growth cone collapse and irreversibly inhibits neurite extension independent of NF-kappaB. The high levels of mTlr3 expression in Mz B cells perhaps contribute to their ability to clear antigen from the blood.
Product Categories/Family for anti-mTLR3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
toll-like receptor 3
NCBI Official Synonym Full Names
toll-like receptor 3
NCBI Official Symbol
Tlr3
NCBI Official Synonym Symbols
AI957183
NCBI Protein Information
toll-like receptor 3
UniProt Protein Name
Toll-like receptor 3
UniProt Gene Name
Tlr3
UniProt Entry Name
TLR3_MOUSE
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Product Notes
The mTLR3 tlr3 (Catalog #AAA78212) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Monoclonal Antibody to mTLR3 (ABM24E5) reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's mTLR3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the mTLR3 tlr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "mTLR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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