IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with MUC16 Recombinant Rabbit Monoclonal Antibody (OCA125/4505R).)
Rabbit anti-Human MUC16/CA125 Monoclonal Antibody | anti-CA125 antibody
MUC16/CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody [Clone OCA125/4505R]
Gene Names
MUC16; CA125
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
MUC16/CA125, Antibody; MUC16/CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody [Clone OCA125/4505R]; MUC16/CA125 (Ovarian Carcinoma Marker); CA125; Cancer antigen 125; MUC16; Mucin16; Ovarian cancer-related tumor marker CA125; anti-CA125 antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit/IgG
Clone Number
OCA125/4505R
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-CA125 antibody
IHC (Immunohistochemistry)
Antibody Type
Recombinant Antibody
Immunogen
Synthetic peptide corresponding to CA125 residues within aa12201 12300 of CA125 was used as an immunogen.
Cellular Localization
Cell Surface and Secreted
Positive Control
MDA-MB-468 cells. Ovarian cancer.
Hu-chromosome Location
19p13.2
Unigene
432676
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with MUC16 Recombinant Rabbit Monoclonal Antibody (OCA125/4505R).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with MUC16 Recombinant Rabbit Monoclonal Antibody (OCA125/4505R).)
Related Product Information for anti-CA125 antibody
CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80% of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
2,353,428 Da
NCBI Official Full Name
mucin-16
NCBI Official Synonym Full Names
mucin 16, cell surface associated
NCBI Official Symbol
MUC16
NCBI Official Synonym Symbols
CA125
NCBI Protein Information
mucin-16; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125
UniProt Protein Name
Mucin-16
UniProt Gene Name
MUC16
UniProt Synonym Gene Names
CA125; MUC-16; CA-125
UniProt Entry Name
MUC16_HUMAN
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Product Notes
The CA125 muc16 (Catalog #AAA216060) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MUC16/CA125 (Ovarian Carcinoma Marker) Recombinant Rabbit Monoclonal Antibody [Clone OCA125/4505R] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MUC16/CA125 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CA125 muc16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MUC16/CA125, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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