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WB (Western Blot)
(Western Blot Analysis of human brain tissue lysate using Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273).)
Rat Myelin Basic Protein Monoclonal Antibody | anti-MBP antibody
Myelin Basic Protein Rat Monoclonal Antibody [Clone MBP/4273]
Reactivity
Apteronotus Leptorhynchus, Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep
Applications
Immunohistochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, Western Blot, Immunocytochemistry, ELISA
Synonyms
Myelin Basic Protein, Antibody; Myelin Basic Protein Rat Monoclonal Antibody [Clone MBP/4273]; GDB; Golli MBP; myelin basic protein; Hemopoietic MBP; HMBPR; HUGO; MLD; Myelin A1 Protein, basic; Myelin Deficient; Myelin membrane encephalitogenic protein; SHI; Shiverer; SP; anti-MBP antibody
Host
Rat
Reactivity
Apteronotus Leptorhynchus, Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
MBP/4273
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Applicable Applications for anti-MBP antibody
IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), WB (Western Blot), ICC (Immunocytochemistry), ELISA
Immunogen
Reacts with human MBP, recognizing epitopes in the 82-87 amino acid region (DENPVV).
Cellular Localization
Myelin membrane, Nucleus
Positive Control
Human brain or astrocytoma tissue.
Research Area
Cardiovascular, Complement System, Developmental Biology, Neuroscience
Preparation and Storage
Antibody with azide - store at 2 to 8 °C. Non-hazardous. No MSDS required.
WB (Western Blot)
(Western Blot Analysis of human brain tissue lysate using Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273).)
WB (Western Blot)
(Western Blot Analysis of human brain tissue lysate using Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273).)
SDS-PAGE
(SDS-PAGE Analysis of Purified Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis of Purified Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273). Confirmation of Purity and Integrity of Antibody.)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human brain stained with Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273).)
IHC (Immunohiostchemistry)
(Formalin-fixed, paraffin-embedded human brain stained with Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human brain stained with Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human brain stained with Myelin Basic Protein Rat Monoclonal Antibody (MBP/4273).)
Related Product Information for anti-MBP antibody
Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30% of the total protein and about 10% of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin. MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas. MBP/4273 recognizes an epitope in the 82-87 region of MBP, useful in clinical identification to detect MBP levels or myelination in human MBP. MBP/4273 is also used in a 2-site ELISA with clone MBP/4275. Both are used interchangeably as capture and detection antibody.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
14-22kDa
NCBI Official Full Name
myelin basic protein
NCBI Official Synonym Full Names
myelin basic protein
NCBI Official Symbol
MBP
NCBI Protein Information
Golli-MBP; myelin basic protein; myelin A1 protein; myelin membrane encephalitogenic protein
UniProt Protein Name
Myelin basic protein
UniProt Gene Name
MBP
UniProt Synonym Gene Names
MBP
UniProt Entry Name
MBP_HUMAN
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Product Notes
The MBP mbp (Catalog #AAA215792) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Myelin Basic Protein Rat Monoclonal Antibody [Clone MBP/4273] reacts with Apteronotus Leptorhynchus, Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's Myelin Basic Protein can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IF (Immunofluorescence), FCM/FACS (Flow Cytometry), WB (Western Blot), ICC (Immunocytochemistry), ELISA. Researchers should empirically determine the suitability of the MBP mbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Myelin Basic Protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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