SDS-PAGE
(SDS PAGE for Nesvacumab)
anti-Human Nesvacumab Monoclonal Antibody | anti-ANGPT2 antibody
Research Grade Nesvacumab
Gene Names
ANGPT2; ANG2; AGPT2
Reactivity
Human
Purity
>95%; Protein A or G purified from cell culture supernatant.
Synonyms
Nesvacumab, Antibody; Research Grade Nesvacumab; REGN-910; ANG-2; ANGPT2; Angiopoietin-2; anti-ANGPT2 antibody
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1-nd
Purity/Purification
>95%; Protein A or G purified from cell culture supernatant.
Form/Format
Liquid. PBS buffer, pH7.4
Concentration
1mg/ml (varies by lot)
Host Species
Human
CAS
1296818-77-3
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
(SDS PAGE for Nesvacumab)
SDS-PAGE
(SDS PAGE for Nesvacumab)
Bioactivity
(Detects Human ANGPT2 in direct ELISAs.)
Bioactivity
(Detects Human ANGPT2 in direct ELISAs.)
Product Categories/Family for anti-ANGPT2 antibody
References
Innovative therapies for neovascular age-related macular degeneration, PMID: 31298960
Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration, PMID: 28756707
A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors, PMID: 26490310
Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer, PMID: 27841282
Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration, PMID: 28756707
A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors, PMID: 26490310
Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer, PMID: 27841282
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,919 Da
NCBI Official Full Name
angiopoietin-2 isoform c
NCBI Official Synonym Full Names
angiopoietin 2
NCBI Official Symbol
ANGPT2
NCBI Official Synonym Symbols
ANG2; AGPT2
NCBI Protein Information
angiopoietin-2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a
UniProt Protein Name
Angiopoietin-2
UniProt Gene Name
ANGPT2
UniProt Synonym Gene Names
ANG-2
UniProt Entry Name
ANGP2_HUMAN
Similar Products
Product Notes
The ANGPT2 angpt2 (Catalog #AAA119958) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Research Grade Nesvacumab reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Nesvacumab, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.