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product-image-AAA249062_WB13.jpg WB (Western Blot) (MCF7 cells were subjected to SDS PAGE followed by western blot with AAA249062 (NFKB1 antibody) at dilution of 1:1000)

Mouse anti-Human NFKB1 Monoclonal Antibody | anti-NFKB1 antibody

Anti-NFKB1 Antibody

Gene Names
NFKB1; KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
>=95% as determined by SDS-PAGE
Protein A+G purification
Synonyms
NFKB1, Antibody; Anti-NFKB1 Antibody; DKFZp686C01211; DNA binding factor KBF1; EBP 1; KBF1; NF kappa B; NFKB p105; NFKB p50; NFKB1; NFKB1;p105; NFKB1;p105;p50; p105; p50; anti-NFKB1 antibody
Ordering
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1G4
Purity/Purification
>=95% as determined by SDS-PAGE
Protein A+G purification
Form/Format
Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Sequence Length
968
Applicable Applications for anti-NFKB1 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Immunogen
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Preparation and Storage
Store at -20 degree C for 24 months. Avoid repeated freeze/thaw cycles.

WB (Western Blot)

(MCF7 cells were subjected to SDS PAGE followed by western blot with AAA249062 (NFKB1 antibody) at dilution of 1:1000)

product-image-AAA249062_WB13.jpg WB (Western Blot) (MCF7 cells were subjected to SDS PAGE followed by western blot with AAA249062 (NFKB1 antibody) at dilution of 1:1000)

IF (Immunofluorescence)

(Immunofluorescent analysis of HepG2 cells using AAA249062 (NFKB1 antibody) at dilution of 1:100)

product-image-AAA249062_IF15.jpg IF (Immunofluorescence) (Immunofluorescent analysis of HepG2 cells using AAA249062 (NFKB1 antibody) at dilution of 1:100)
Related Product Information for anti-NFKB1 antibody
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra-and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed MW: 105kDa; 50kDa
NCBI Official Full Name
nuclear factor NF-kappa-B p105 subunit isoform 2 proprotein
NCBI Official Synonym Full Names
nuclear factor kappa B subunit 1
NCBI Official Symbol
NFKB1
NCBI Official Synonym Symbols
KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta
NCBI Protein Information
nuclear factor NF-kappa-B p105 subunit
UniProt Protein Name
Nuclear factor NF-kappa-B p105 subunit
UniProt Gene Name
NFKB1
UniProt Entry Name
NFKB1_HUMAN

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Product Notes

The NFKB1 nfkb1 (Catalog #AAA249062) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-NFKB1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NFKB1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NFKB1 nfkb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NFKB1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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