anti-HRSV-A Nirsevimab Monoclonal Antibody | anti-F antibody

Research Grade Nirsevimab

Cat. Num. AAA120146

• Reactivity: HRSV-A
• Purity: >95%; Protein A or G purified from cell culture supernatant.
• Synonyms: Nirsevimab, Antibody; Research Grade Nirsevimab; MEDI-8897; MEDI8897; F; Fusion glycoprotein F0; anti-F antibody

• Reactivity: HRSV-A
• Clonality: Monoclonal
• Isotype: IgG1-kappa
• Purity/Purification: >95%; Protein A or G purified from cell culture supernatant.
• Form/Format: Liquid. PBS buffer, pH7.4
• Concentration: 1mg/ml (varies by lot)

• Host Species: Humanized
• CAS: 1989556-22-0
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Preparation and Storage: Store at +4 degree C short term (1-2 weeks). Store at -20 degree C 12 months. Store at -80 degree C long term.; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

SDS-PAGE

(SDS PAGE for Nirsevimab)

Bioactivity

(Detects Human F/Fusion glycoprotein F0 in direct ELISAs.)

Product Categories/Family for anti-F antibody

Research Biosimilar

References

Single-dose nirsevimab prevents RSV infection, PMID: 33342497
Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants, PMID: 32730699
Coadministration of Anti-Viral Monoclonal Antibodies With Routine Pediatric Vaccines and Implications for Nirsevimab Use: A White Paper, PMID: 34456918
Global molecular diversity of RSV - the "INFORM RSV" study, PMID: 32591017
Nirsevimab reduces medically attended RSV-associated lower respiratory tract infection and hospitalisations in healthy pre-term infants, PMID: 33597216

NCBI and Uniprot Product Information

• NCBI GI #: 138251
• UniProt Accession #: P03420; P88811
• Molecular Weight: 63,453 Da
• NCBI Official Full Name: Fusion glycoprotein F0
• UniProt Protein Name: Fusion glycoprotein F0
• UniProt Gene Name: F
• UniProt Synonym Gene Names: Protein F
• UniProt Entry Name: FUS_HRSVA